Compile Data Set for Download or QSAR
Report error Found 186 Enz. Inhib. hit(s) with all data for entry = 10665
TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557893(US11365191, Example 3)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557910(N-(2-((trans)-4-(4-fluoro-2-methylphenyl)cyclohexy...)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557911(N-(2-((trans)-4-(2-chloro-6-fluorophenyl)cyclohexy...)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557912(US11365191, Example 25)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557913(US11365191, Example 27)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557915(US11365191, Example 53)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557916(US11365191, Example 54)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557917(US11365191, Example 55)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557918(N-(2-((cis)-4-(2-chloro-4-fluorophenyl)cyclohexyl)...)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557919(US11365191, Example 57)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557920(US11365191, Example 61)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557921(US11365191, Example 64)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557922(US11365191, Example 76)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557923(N-(2-((trans)-4-(3-chloro-5-fluoropyridin-2-yl)cyc...)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557924(US11365191, Example 93)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557925(US11365191, Example 158)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557926(US11365191, Example 161)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557927(US11365191, Example 4)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557928(US11365191, Example 5)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557929(US11365191, Example 7)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557930(N-(2-((trans)-4-(2,6-dichlorophenyl)cyclohexyl)eth...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557931(US11365191, Example 9)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557932(N-(2-((trans)-4-(2,4-difluorophenyl)cyclohexyl)eth...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557933(US11365191, Example 17)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557934(US11365191, Example 19)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557935(US11365191, Example 21)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557936(US11365191, Example 26)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557937(4-((2-((trans)-4-(2-chloro-4,6-difluorophenyl)cycl...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557938(US11365191, Example 37)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557939(4-((2-((trans)-4-(4-fluoro-2-(trifluoromethyl)phen...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557940(4-((2-((trans)-4-(2,4-difluoro-6-methylphenyl)cycl...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557941(US11365191, Example 43)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557942(US11365191, Example 45)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557943(N-Methyl-4-({2-[(trans)-4-[4-fluoro-2-(trifluorome...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557944(US11365191, Example 49 | US11365191, Example 47)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557945(US11365191, Example 52)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557946(US11365191, Example 60)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557947(4-((2-((trans)-4-(3-chloro-5-fluoropyridin-2-yl)cy...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557948(US11365191, Example 63)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557949(US11365191, Example 66)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557950(US11365191, Example 70)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557951(US11365191, Example 77)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557952(US11365191, Example 79)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557953(US11365191, Example 82)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557954(4-((2-((trans)-4-(3-chloro-5-fluoropyridin-4-yl)cy...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557955(4-((2-((trans)-4-(3-chloro-5-fluoropyridin-2-yl)cy...)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557956(US11365191, Example 95)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557957(US11365191, Example 97)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557958(US11365191, Example 99)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557959(US11365191, Example 101)
Affinity DataIC50: 5.5nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

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