Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with all data for entry = 10660
LigandPNGBDBM557721((1S,3'R,6'R,7'R,11'S,12'R)-7'-((2r,3aR,6aS)- 5-ace...)
Affinity DataIC50: 0.0980nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557798(US11364248, Example 94 | US11364248, Example 95 | ...)
Affinity DataIC50: 0.152nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
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LigandPNGBDBM557787((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50: 0.175nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557796(US11364248, Example 92 | (1S,3'R,6'R,7'S,11'S,12'S...)
Affinity DataIC50: 0.184nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557721((1S,3'R,6'R,7'R,11'S,12'R)-7'-((2r,3aR,6aS)- 5-ace...)
Affinity DataIC50: 0.194nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
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LigandPNGBDBM557778(US11364248, Example 74 | (1S,3'R,6'S,7'S,12'R)-6-c...)
Affinity DataIC50: 0.196nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557740(US11364248, Example 38 | US11364248, Example 39 | ...)
Affinity DataIC50: 0.217nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557776(US11364248, Example 72 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.217nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557747(US11364248, Example 43)
Affinity DataIC50: 0.251nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
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LigandPNGBDBM557725(US11364248, Example 21 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.261nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
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LigandPNGBDBM557756(US11364248, Example 53 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.267nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557715(US11364248, Example 12 | US11364248, Example 14 | ...)
Affinity DataIC50: 0.290nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557802((1S,3′R,6′R,7′S,8′E,11R...)
Affinity DataIC50: 0.308nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557764((1S,3′R,6′R,7′S,11′S,12...)
Affinity DataIC50: 0.319nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557789(US11364248, Example 85 | (1S,3'R,6'R,7'S,10'S,11'S...)
Affinity DataIC50: 0.331nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557750(US11364248, Example 46)
Affinity DataIC50: 0.340nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
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LigandPNGBDBM557772((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50: 0.347nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557731((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-(...)
Affinity DataIC50: 0.370nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557735((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (3,...)
Affinity DataIC50: 0.374nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557740(US11364248, Example 38 | US11364248, Example 39 | ...)
Affinity DataIC50: 0.375nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557715(US11364248, Example 12 | US11364248, Example 14 | ...)
Affinity DataIC50: 0.382nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557784((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-amino-5- (hyd...)
Affinity DataIC50: 0.382nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557762(US11364248, Example 58 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.439nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557724((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-11',12'- dimet...)
Affinity DataIC50: 0.444nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557786(US11364248, Example 86 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.448nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557794((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (di...)
Affinity DataIC50: 0.453nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557766((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50: 0.455nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557801((1S,3′R,6′R,7′S,8′E,11R...)
Affinity DataIC50: 0.459nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557729(US11364248, Example 26 | (1S,3'R,6'R,7'R,11'S,12'R...)
Affinity DataIC50: 0.473nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557732((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(trans- 5-(...)
Affinity DataIC50: 0.477nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557756(US11364248, Example 53 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.490nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557713(US11364248, Example 35 | US11364248, Example 15 | ...)
Affinity DataIC50: 0.490nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557754((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50: 0.492nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557774((1S,3'R,6'R,7'S,11'S,12'R)-6-chloro-7'-(cis-5- (cy...)
Affinity DataIC50: 0.535nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557740(US11364248, Example 38 | US11364248, Example 39 | ...)
Affinity DataIC50: 0.537nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557715(US11364248, Example 12 | US11364248, Example 14 | ...)
Affinity DataIC50: 0.555nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557798(US11364248, Example 94 | US11364248, Example 95 | ...)
Affinity DataIC50: 0.557nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557776(US11364248, Example 72 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.568nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557751(N-(cis-2-((1S,3'R,6'R,7'S,11'S,12'R)-6- chloro-11'...)
Affinity DataIC50: 0.568nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557744((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-amino-5- (hyd...)
Affinity DataIC50: 0.577nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557752(US11364248, Example 49 | (1S,3'R,6'R,7'S,11'S,12'R...)
Affinity DataIC50: 0.590nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557737((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'- ((2S,4S)-4...)
Affinity DataIC50: 0.612nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557745(US11364248, Example 42 | US11364248, Example 41)
Affinity DataIC50: 0.617nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557704(US11364248, Example 1)
Affinity DataIC50: 0.627nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557722(US11364248, Example 17)
Affinity DataIC50: 0.645nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557778(US11364248, Example 74 | (1S,3'R,6'S,7'S,12'R)-6-c...)
Affinity DataIC50: 0.657nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557784((1S,3'R,6'R,7'S,11'S,12'R)-7'-(cis-5-amino-5- (hyd...)
Affinity DataIC50: 0.704nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557728((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-11',12'- dimet...)
Affinity DataIC50: 0.709nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557760((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50: 0.742nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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LigandPNGBDBM557754((1S,3'R,6'R,7'R,11'S,12'R)-6-chloro-7'-(cis-5- (3-...)
Affinity DataIC50: 0.754nMAssay Description:The inhibition of the Mcl-1/Bim interaction was measured using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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