Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 10631
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555732(US11345676, Example 28 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
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TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555722(US11345676, Example 18 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555723(US11345676, Example 19 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
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TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555705(US11345676, Example 1 | US11345676, Compound 1-179)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
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TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555725(US11345676, Example 21 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555727(US11345676, Example 23 | US11345676, Compound 1-22...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555729(US11345676, Example 25 | US11345676, Compound 1-22...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555730(US11345676, Example 26 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555731(US11345676, Example 27 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555724(US11345676, Example 20 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555713(US11345676, Compound 1-338 | US11345676, Example 9...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555735(US11345676, Example 32 | US11345676, Compound 1-34...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555736(US11345676, Example 33 | US11345676, Compound 1-34...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555738(US11345676, Example 35 | US11345676, Compound 1-34...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM555722(US11345676, Example 18 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM555723(US11345676, Example 19 | US11345676, Compound 1-33...)
Affinity DataIC50: 300nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM555726(US11345676, Example 22 | US11345676, Compound 2-1)
Affinity DataIC50: 300nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555713(US11345676, Compound 1-338 | US11345676, Example 9...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555706(US11345676, Example 2 | US11345676, Compound 1-23)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555708(US11345676, Example 4 | US11345676, Compound 1-181)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555709(US11345676, Example 5 | US11345676, Compound 1-210)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555710(US11345676, Example 6 | US11345676, Compound 1-211)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555711(US11345676, Example 7 | US11345676, Compound 1-213)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555712(US11345676, Example 8 | US11345676, Compound 1-217)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555714(US11345676, Example 10 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555715(US11345676, Example 11 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555716(US11345676, Example 12 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555717(US11345676, Example 13 | US11345676, Compound 1-30...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555718(US11345676, Example 14 | US11345676, Compound 1-31...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555719(US11345676, Example 15 | US11345676, Compound 1-31...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555720(US11345676, Example 16 | US11345676, Compound 1-31...)
Affinity DataIC50: 300nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555721(US11345676, Example 17 | US11345676, Compound 1-32...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555733(US11345676, Example 29 | US11345676, Compound 1-33...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555728(US11345676, Example 24 | US11345676, Compound 1-22...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555737(US11345676, Example 34 | US11345676, Compound 1-34...)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555707(US11345676, Example 3 | US11345676, Compound 1-24)
Affinity DataIC50: 650nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Pharmakea

US Patent
LigandPNGBDBM555726(US11345676, Example 22 | US11345676, Compound 2-1)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 3: The ability of test compounds to inhibit ASK1 kinase activity was determined using the luminescent ADP-Glo Kinase Assay and Myelin Basic Pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM555714(US11345676, Example 10 | US11345676, Compound 1-30...)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 4: LOXL2 amine oxidase activity was evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
Go to US Patent