Compile Data Set for Download or QSAR
Report error Found 742 Enz. Inhib. hit(s) with all data for entry = 10581
TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552067(US11312727, Compound 1)
Affinity DataEC50:  43nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552068(15-hydroxy-2-phenyl-12,13,14,16-tetrahydro-11H-1(1...)
Affinity DataEC50:  354nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552069(4-hydroxy-16-phenyl-7,8,9,10,11,16-hexahydro-6,17-...)
Affinity DataEC50:  48nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552070(US11312727, Compound 5)
Affinity DataEC50:  26nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552071(US11312727, Compound 20B | US11312727, Compound 5A)
Affinity DataEC50:  8nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552072((18R,Z)-12-hydroxy-18-phenyl-6,9-dihydro-18H-10,17...)
Affinity DataEC50: >1.00E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552073((*E)-15-hydroxy-2-phenyl-12,13,14,16-tetrahydro-11...)
Affinity DataEC50:  6.15E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552074(US11312727, Compound 8)
Affinity DataEC50:  59nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552075(US11312727, Compound 8A)
Affinity DataEC50:  13nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552076(12-hydroxy-18-phenyl-6,7,8,9-tetrahydro-18H-10,17-...)
Affinity DataEC50:  4.13E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552077(15-hydroxy-2-phenyl-12,13,14,16-tetrahydro-11H-4-o...)
Affinity DataEC50:  453nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552078(US11312727, Compound 10A)
Affinity DataEC50: >1.00E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552079(US11312727, Compound 10B)
Affinity DataEC50:  13nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552080(15-hydroxy-2-(pyridin-2-yl)-12,13,14,16-tetrahydro...)
Affinity DataEC50:  363nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552081(4-hydroxy-16-(pyridin-2-yl)-7,8,9,10,11,16-hexahyd...)
Affinity DataEC50:  86nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552069(4-hydroxy-16-phenyl-7,8,9,10,11,16-hexahydro-6,17-...)
Affinity DataEC50:  19nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552083((*E)-15-hydroxy-2-phenyl-12,13,14,16-tetrahydro-11...)
Affinity DataEC50:  48nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552084(US11312727, Compound 15)
Affinity DataEC50:  635nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552085(US11312727, Compound 16)
Affinity DataEC50:  142nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552086((E)-15-hydroxy-2-phenyl-12,13,14,16-tetrahydro-11H...)
Affinity DataEC50:  77nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552087(12-hydroxy-18-phenyl-5,8,9,18-tetrahydro-10,17-met...)
Affinity DataEC50:  7.91E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552088((*Z)-15-hydroxy-2-phenyl-12,13,14,16-tetrahydro-11...)
Affinity DataEC50:  260nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552072((18R,Z)-12-hydroxy-18-phenyl-6,9-dihydro-18H-10,17...)
Affinity DataEC50:  93nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552071(US11312727, Compound 20B | US11312727, Compound 5A)
Affinity DataEC50:  1.00E+4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552091(US11312727, Compound 52A | US11312727, Compound 21...)
Affinity DataEC50:  5nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552092(US11312727, Compound 52B | (17*R,*Z)-4-hydroxy-16-...)
Affinity DataEC50:  815nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552093(US11312727, Compound 22A)
Affinity DataEC50:  9.54E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552094((18*R,Z)-2-fluoro-12-hydroxy-18-phenyl-6,9-dihydro...)
Affinity DataEC50:  12nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552095(US11312727, Compound 23A)
Affinity DataEC50:  5.50E+4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552096((18*R)-12-hydroxy-18-phenyl-5,6,7,8,9,18-hexahydro...)
Affinity DataEC50:  1.22E+4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552097(US11312727, Compound 24A)
Affinity DataEC50:  3.96E+4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552098((18*R,*Z)-12-hydroxy-18-phenyl-5,6,9,18-tetrahydro...)
Affinity DataEC50:  1.53E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552099(US11312727, Compound 25A)
Affinity DataEC50:  9.80E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552100((18*R,Z)-2-fluoro-18-(3-fluorophenyl)-12-hydroxy-6...)
Affinity DataEC50:  11nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552101(US11312727, Compound 26A)
Affinity DataEC50:  394nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552102((18*R,*Z)-12-hydroxy-18-(pyridin-3-yl)-6,9-dihydro...)
Affinity DataEC50:  4.01E+4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552103(US11312727, Compound 27A)
Affinity DataEC50:  94nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552104((18*R,*Z)-12-hydroxy-18-phenyl-6,9-dihydro-18H-10,...)
Affinity DataEC50:  4.57E+4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552105(US11312727, Compound 28A)
Affinity DataEC50:  5.95E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552106((Compound 28A) and | US11312727, Compound 28B)
Affinity DataEC50:  6nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552107(US11312727, Compound 29AA)
Affinity DataEC50: >3.00E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552108((9*R, 18*R, E)-12-hydroxy-9-methyl-18-phenyl-6,9-d...)
Affinity DataEC50:  8nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552109(US11312727, Compound 29AB)
Affinity DataEC50:  5.70nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552110(US11312727, Compound 29BA)
Affinity DataEC50:  1.71E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552111(US11312727, Compound 30A)
Affinity DataEC50: >1.00E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552112((18*R)-2-fluoro-12-hydroxy-18-phenyl-6,7,8,9-tetra...)
Affinity DataEC50:  15nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
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TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552113((19bR,Z)-4-hydroxy-8,9,15,19b-tetrahydro-7H,14H-13...)
Affinity DataEC50:  4nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552114(US11312727, Compound 32A)
Affinity DataEC50: >1.00E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552115((18*R)-2-fluoro-18-(3-fluorophenyl)-12-hydroxy-6,7...)
Affinity DataEC50:  25nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetPolymerase basic protein 2(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Janssen Biopharma

US Patent
LigandPNGBDBM552116(US11312727, Compound 33A)
Affinity DataEC50: >1.00E+3nMAssay Description:Human lung carcinoma A549 cells (ATCC, Manassas, Va.) were plated at a density of 5×104 cells/mL (10×103 cells/well) in assay media (Ham's F12 me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

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