Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 10443
TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535853(N-(3-amino-6-phenylpyridin-2-yl)nicotinamide | US1...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535879(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-((2-(...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535878(N-(3-amino-6-(thiophen-2-yl)pyridin-2-yl)-6-(4-met...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535878(N-(3-amino-6-(thiophen-2-yl)pyridin-2-yl)-6-(4-met...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535877(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-am...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535877(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-am...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535876(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(pipe...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
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TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535871(N-(3-amino-6-phenylpyridin-2-yl)-2-(cyclopropylami...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535870(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-2-(4-me...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535869(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-2-morph...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535867(N-(3-amino-6-phenylpyridin-2-yl)-2-(4-methylpipera...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535852(N-(3-amino-6-phenylpyridin-2-yl)-6-(4-methylpipera...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535854(US11241428, Example 3)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535859(N-(3-amino-6-phenylpyridin-2-yl)-6-morpholinonicot...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 200nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535876(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(pipe...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535875(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-cyclo...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535874(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(3-cy...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535873(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-[2,3...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535862(N-(3-amino-6-(4-methoxyphenyl)pyridin-2-yl)-6-(4-m...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535863(N-(5-amino-[2,4′-bipyridin]-6-yl)-6-(4-methy...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Medibiofarma

US Patent
LigandPNGBDBM535864(N-(3-amino-6-(3,4-difluorophenyl)pyridin-2-yl)-6-(...)
Affinity DataIC50: 600nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535876(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(pipe...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535878(N-(3-amino-6-(thiophen-2-yl)pyridin-2-yl)-6-(4-met...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Medibiofarma

US Patent
LigandPNGBDBM535878(N-(3-amino-6-(thiophen-2-yl)pyridin-2-yl)-6-(4-met...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535878(N-(3-amino-6-(thiophen-2-yl)pyridin-2-yl)-6-(4-met...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535877(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-am...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Medibiofarma

US Patent
LigandPNGBDBM535877(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-am...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Medibiofarma

US Patent
LigandPNGBDBM535876(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(pipe...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 2.55E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Medibiofarma

US Patent
LigandPNGBDBM535876(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(pipe...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535877(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-am...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535876(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(pipe...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535860(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-morph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535861(N-(3-amino-6-(4-fluorophenyl)pyridin-2-yl)-6-(4-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Medibiofarma

US Patent
LigandPNGBDBM535872(US11241428, Example 17)
Affinity DataIC50: 5.00E+4nMAssay Description:The inhibitory activities of compounds of present invention were determined using biochemical HDAC assays (Reaction Biology Corp. biochemical assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2022
Entry Details
Go to US Patent