Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 10431
TargetHistone deacetylase 6(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1 | US12076401, Compound ...)
Affinity DataIC50: 6.40nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
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TargetHistone deacetylase 6(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3 | US12076401, Compound ...)
Affinity DataIC50: 14.5nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 15nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1 | US12076401, Compound ...)
Affinity DataIC50: 19nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 68nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3 | US12076401, Compound ...)
Affinity DataIC50: 79nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1 | US12076401, Compound ...)
Affinity DataIC50: 130nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534825(US11236052, Compound ID #1 | US12076401, Compound ...)
Affinity DataIC50: 137nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 385nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3 | US12076401, Compound ...)
Affinity DataIC50: 445nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534955(US11236052, Compound ID #3 | US12076401, Compound ...)
Affinity DataIC50: 3.12E+3nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
Translational Drug Development

US Patent
LigandPNGBDBM534842(US11236052, Compound ID #2 | US12076401, Compound ...)
Affinity DataIC50: 3.56E+3nMAssay Description:Purified histone deacetylase enzymes 1, 3, 6, 10 were incubated with fluorescently labeled substrate and test compounds in a standardized reaction mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
Go to US Patent