Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 10421
TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534617(US11229636, Compound 105 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534635(US11229636, Compound 47 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534637(US11229636, Compound 50 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534638(2-(4-(ethylsulfonyl)phenyl)-N-(6-(5-methoxypyrimid...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534614(US11229636, Compound 2 | 2-(4-(ethylsulfonyl)pheny...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534640(US11229636, Compound 62 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534643(US11229636, Compound 86 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534649(US11229636, Compound 92 | N-(6-(5-chloroimidazo[1,...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534616(US11229636, Compound 104 | N-(6-(2,6-dimethylpyrim...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534639(US11229636, Compound 61 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534625(US11229636, Compound 107 | N-(6-(2,6-dimethylpyrim...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534627(US11229636, Compound 109 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534638(2-(4-(ethylsulfonyl)phenyl)-N-(6-(5-methoxypyrimid...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534658(US11229636, Compound 128 | N-(7-(2,6-dimethylpyrim...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534659(US11229636, Compound 132 | N-(6-(2-ethyl-6-methylp...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534660(US11229636, Compound 133 | N-(6-(2,6-diethylpyrimi...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534661(US11229636, Compound 135 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534631(US11229636, Compound 42 | N-(6-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534616(US11229636, Compound 104 | N-(6-(2,6-dimethylpyrim...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534617(US11229636, Compound 105 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534618(US11229636, Compound 12 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534627(US11229636, Compound 109 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534619(US11229636, Compound 15 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534623(US11229636, Compound 22 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534632(US11229636, Compound 43 | N-(4,6-dimethyl-6-(1-met...)
Affinity DataIC50: 150nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534647(US11229636, Compound 90 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534615(US11229636, Compound 6 | 2-(4-(ethylsulfonyl)pheny...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534620(US11229636, Compound 16 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534621(US11229636, Compound 19 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534622(US11229636, Compound 21 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534645(US11229636, Compound 88 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534644(US11229636, Compound 87 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534625(US11229636, Compound 107 | N-(6-(2,6-dimethylpyrim...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534641(US11229636, Compound 84 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534626(US11229636, Compound 29 | N-(6-(4,6-dimethylpyrimi...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534629(US11229636, Compound 35 | N-(6-(6-methoxypyridazin...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534636(US11229636, Compound 49 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 225nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534646(US11229636, Compound 89 | N-(6-(3-hydroxypyridin-2...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534648(US11229636, Compound 91 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534624(US11229636, Compound 26 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534642(US11229636, Compound 85 | 2-(4-(ethylsulfonyl)phen...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534625(US11229636, Compound 107 | N-(6-(2,6-dimethylpyrim...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534627(US11229636, Compound 109 | 2-(4-(ethylsulfonyl)phe...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534638(2-(4-(ethylsulfonyl)phenyl)-N-(6-(5-methoxypyrimid...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534628(US11229636, Compound 34 | N-(4,6-dimethyl-6-(6-met...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetNuclear receptor ROR-gamma(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM534633(US11229636, Compound 46 | N-(6-(3,5-dimethyl-1H-py...)
Affinity DataIC50: 300nMAssay Description:ROR gamma radioligand binding was performed using 3H 25-Hydroxycholesterol in a competitive displacement assay using dextran charcoal method. Using 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent