Compile Data Set for Download or QSAR
Report error Found 131 Enz. Inhib. hit(s) with all data for entry = 10368
TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 0.300nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 1.20nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 1.80nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 2nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 4nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 5nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 6.20nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 7.10nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: 7.10nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 8.90nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 10nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM531096(US11207431, Example 16 | US11890356, Example 16)
Affinity DataIC50: 12nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 13nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM531089(US11207431, Example 9 | US11890356, Example 9)
Affinity DataIC50: 13.6nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 15nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM50369345(CHEMBL4165724 | US11207431, Example 1 | US11890356...)
Affinity DataIC50: 16nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM323718(US10188756, Compound CN149 | US11207431, Example B)
Affinity DataIC50: 17nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 20nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 22nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 23nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM323718(US10188756, Compound CN149 | US11207431, Example B)
Affinity DataIC50: 23nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 24nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 25nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM531093(US11207431, Example 13 | US11890356, Example 13)
Affinity DataIC50: 26.7nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 5(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 7(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 11(Human)
The General Hospital

US Patent
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 5(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 7(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetPolyamine deacetylase HDAC10(Human)
The General Hospital

US Patent
LigandPNGBDBM323718(US10188756, Compound CN149 | US11207431, Example B)
Affinity DataIC50: 33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 34nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM531097(US11207431, Example 17 | US11890356, Example 17)
Affinity DataIC50: 35nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 7(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 36nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 41nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 46nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
The General Hospital

US Patent
LigandPNGBDBM323709(US10188756, Compound CN133 | US11207431, Martinost...)
Affinity DataIC50: 48nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 48nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 51nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 9(Human)
The General Hospital

US Patent
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50: 52nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
Go to US Patent

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