Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 10243
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM522185(US11161835, Compound Formula (Ih))
Affinity DataIC50: 1.20E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458106(US10752613, Compound Formula (Ii) | US11161835, Co...)
Affinity DataIC50: 1.30E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM522179(US11161835, Compound Formula (Ib))
Affinity DataIC50: 1.40E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM522184(US11161835, Compound Formula (Ig))
Affinity DataIC50: 2.20E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM522181(US11161835, Compound Formula (Id))
Affinity DataIC50: 5.90E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM522174(US11161815, Example 30)
Affinity DataIC50: 6.50E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM522180(US11161835, Compound Formula (Ic))
Affinity DataIC50: 1.22E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458102(US10752613, Compound Formula (Ie) | US11161835, Co...)
Affinity DataIC50: 1.45E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458107(US10752613, Compound Formula (Ij) | US11161835, Co...)
Affinity DataIC50: 1.63E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458110(US10752613, Compound Formula (Im) | US11161835, Co...)
Affinity DataIC50: 2.52E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458109(US10752613, Compound Formula (Il) | US11161835, Co...)
Affinity DataIC50: 6.79E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458108(US10752613, Compound Formula (Ik) | US11161835, Co...)
Affinity DataIC50: 6.80E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM458103(US10752613, Compound Formula (If) | US11161835, Co...)
Affinity DataIC50: 7.01E+4nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandPNGBDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 3.00E+5nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent