Compile Data Set for Download or QSAR
Report error Found 130 Enz. Inhib. hit(s) with all data for entry = 10235
TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397502(US9994546, Example 1 | (1-{4-[(trans-2-Phenylcyclo...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397503(US9994546, Example 2 | (1-Methyl-3-{4-[(trans-2-ph...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397504(US9994546, Example 3 | (3-{4-[(trans-2-Phenylcyclo...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397505(US9994546, Example 4 | (1-Benzyl-3-{4-[(trans-2-ph...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397506(US9994546, Example 5 | 3-(3-(Cyanomethyl)-3-{4-[(t...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397507(US9994546, Example 6 | (1-Acetyl-3-{4-[(trans-2-ph...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397508(US9994546, Example 7 | (1-Benzoyl-3-{4-[(trans-2-p...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397509(US9994546, Example 8 | Methyl 3-(cyanomethyl)-3-{4...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397510(US9994546, Example 9 | (1-(Methylsulfonyl)-3-{4-[(...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397511(US9994546, Example 10 | 2-(3-(Cyanomethyl)-3-{4-[(...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397513(US9994546, Example 12 | 2-(3-(Cyanomethyl)-3-{4-[(...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397514(US9994546, Example 13 | 4-(3-(Cyanomethyl)-3-{4-[(...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397515(US9994546, Example 14 | [1-(3-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397516(US9994546, Example 15 | (1′-(Ethylsulfonyl)-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
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Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397517(US9994546, Example 16 | [4-(3-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397518(US9994546, Example 17 | [1-Methyl-4-(3-{[(trans-2-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397519(US9994546, Example 18 | [1-Acetyl-4-(3-{[(trans-2-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397520(US9994546, Example 19 | [1-(4-Fluorobenzoyl)-4-(3-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397521(US9994546, Example 20 | [1-(Methylsulfonyl)-4-(3-{...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397522(US9994546, Example 21 | [4-(3-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397523(US9994546, Example 22 | Ethyl 4-(cyanomethyl)-4-(3...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397524(US9994546, Example 23 | 4-(Cyanomethyl)-N,N-dimeth...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397525(US9994546, Example 24 | 4-(Cyanomethyl)-N-isopropy...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397526(US9994546, Example 25 | 4-(Cyanomethyl)-N-(4-fluor...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397527(US9994546, Example 26 | (3-{[(trans-2-Phenylcyclop...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397528(US9994546, Example 27 | 4-(3′-(Cyanomethyl)-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397529(US9994546, Example 28 | N-{[1-(1-Methylpiperidin-4...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397530(US9994546, Example 29 | Trans-2-phenyl-N-{[1-(1-ph...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397531(US9994546, Example 30 | 1-Phenyl-4-(3-{[(trans-2-p...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397533(US9994546, Example 32 | [1-(4-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397534(US9994546, Example 33 | [3-(4-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397535(US9994546, Example 34 | 2-[3-(Cyanomethyl)-3-(4-{[...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397536(US9994546, Example 35 | 4-[3-(Cyanomethyl)-3-(4-{[...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397537(US9994546, Example 36 | {3-(4-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397538(US9994546, Example 37 | {3-(4-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397539(US9994546, Example 38 | 2-Chloro-6-[3-(cyanomethyl...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397540(US9994546, Example 39 | 2-[3-(Cyanomethyl)-3-(4-{[...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397541(US9994546, Example 40 | 4-[3-(Cyanomethyl)-3-(4-{[...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397542(US9994546, Example 41 | Methyl 3-(cyanomethyl)-3-(...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397543(US9994546, Example 42 | 3-(Cyanomethyl)-N-(2,4-dif...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397544(US9994546, Example 43 | N-(3-Chloro-2-fluorophenyl...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397545(US9994546, Example 44 | [1-(3,5-Difluorobenzoyl)-3...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397546(US9994546, Example 45 | [1-Benzoyl-3-(4-{[(trans-2...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397547(US9994546, Example 46 | [1-(2-Fluorobenzoyl)-3-(4-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
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US Patent
LigandPNGBDBM397548(US9994546, Example 47 | [1-(3-Fluorobenzoyl)-3-(4-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397549(US9994546, Example 48 | [1-(4-Fluorobenzoyl)-3-(4-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397550(US9994546, Example 49 | [1-Methyl-3-(4-{[(trans-2-...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397551(US9994546, Example 50 | [3-(4-{[(trans-2-Phenylcyc...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397552(US9994546, Example 51 | N-Methyl-2-(3-(4-((trans-2...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Incyte

US Patent
LigandPNGBDBM397553(US9994546, Example 52 | N,N-Dimethyl-2-(3-(4-((tra...)
Affinity DataIC50: 100nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

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