Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 10209
TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520269(US11130750, Example 1)
Affinity DataIC50: 500nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
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Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
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US Patent
LigandPNGBDBM78934(MLS001056800 | Mibefradil dihydrochloride hydrate ...)
Affinity DataIC50: 720nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM78934(MLS001056800 | Mibefradil dihydrochloride hydrate ...)
Affinity DataIC50: 720nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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PDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520274(US11130750, Example 6)
Affinity DataIC50: 2.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
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US Patent
LigandPNGBDBM520270(US11130750, Example 2)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520282(US11130750, Example 21B)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
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US Patent
LigandPNGBDBM520281(US11130750, Example 21A | (4S)-3-(2-((3-(4,7-Dimet...)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
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US Patent
LigandPNGBDBM520271(US11130750, Example 3)
Affinity DataIC50: 5.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520273(US11130750, Example 5)
Affinity DataIC50: 6.00E+3nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520280(US11130750, Example 16)
Affinity DataIC50: 7.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520278(US11130750, Example 12)
Affinity DataIC50: 7.90E+3nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
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US Patent
LigandPNGBDBM520276(US11130750, Example 10)
Affinity DataIC50: 9.00E+3nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520277(US11130750, Example 11)
Affinity DataIC50: 1.20E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520274(US11130750, Example 6)
Affinity DataIC50: 1.30E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520282(US11130750, Example 21B)
Affinity DataIC50: 1.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520281(US11130750, Example 21A | (4S)-3-(2-((3-(4,7-Dimet...)
Affinity DataIC50: 1.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
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US Patent
LigandPNGBDBM520270(US11130750, Example 2)
Affinity DataIC50: 1.60E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520279(US11130750, Example 15)
Affinity DataIC50: 1.80E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520269(US11130750, Example 1)
Affinity DataIC50: 1.90E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520280(US11130750, Example 16)
Affinity DataIC50: 1.90E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520273(US11130750, Example 5)
Affinity DataIC50: 1.90E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520272(US11130750, Example 4)
Affinity DataIC50: 2.00E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520272(US11130750, Example 4)
Affinity DataIC50: 2.40E+4nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520271(US11130750, Example 3)
Affinity DataIC50: 2.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520275(US11130750, Example 9)
Affinity DataIC50: 2.60E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520279(US11130750, Example 15)
Affinity DataIC50: 2.70E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520277(US11130750, Example 11)
Affinity DataIC50: 3.00E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent