Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 10173
TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518444(US11124500, Example 35 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 1.59nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518444(US11124500, Example 35 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 2.63nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518415(US11124500, Example 9 | 6-[1-[1-(2-Hydroxyethyl)-4...)
Affinity DataIC50: 3.58nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518442(US11124500, Example 33 | 4-[1-(Azetidin-3-yl)pyraz...)
Affinity DataIC50: 3.63nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518418(US11124500, Example 12 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 3.65nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518443(US11124500, Example 34 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 3.71nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518418(US11124500, Example 12 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 3.87nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518445(US11124500, Example 36 | [(2R)-1-[4-[1-(1-Methylaz...)
Affinity DataIC50: 3.98nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518435(US11124500, Example 27 | 6-[1-(3-Hydroxy-4-piperid...)
Affinity DataIC50: 4.63nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518432(US11124500, Example 24b)
Affinity DataIC50: 4.89nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518442(US11124500, Example 33 | 4-[1-(Azetidin-3-yl)pyraz...)
Affinity DataIC50: 4.90nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518417(US11124500, Example 11 | 6-[1-(2-Hydroxyethyl)pyra...)
Affinity DataIC50: 5.23nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518443(US11124500, Example 34 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 5.41nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518413(US11124500, Example 7 | 2-[(2S,3R)-3-Hydroxy-2-met...)
Affinity DataIC50: 6.02nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518431(US11124500, Example 24a)
Affinity DataIC50: 6.06nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518415(US11124500, Example 9 | 6-[1-[1-(2-Hydroxyethyl)-4...)
Affinity DataIC50: 6.26nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518432(US11124500, Example 24b)
Affinity DataIC50: 6.75nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518430(US11124500, Example 24 | 6-[1-(2,3-Dihydroxypropyl...)
Affinity DataIC50: 7.29nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518419(US11124500, Example 13 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 7.69nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518430(US11124500, Example 24 | 6-[1-(2,3-Dihydroxypropyl...)
Affinity DataIC50: 7.91nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518417(US11124500, Example 11 | 6-[1-(2-Hydroxyethyl)pyra...)
Affinity DataIC50: 8.03nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518435(US11124500, Example 27 | 6-[1-(3-Hydroxy-4-piperid...)
Affinity DataIC50: 9.21nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518431(US11124500, Example 24a)
Affinity DataIC50: 9.99nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518445(US11124500, Example 36 | [(2R)-1-[4-[1-(1-Methylaz...)
Affinity DataIC50: 10nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518410(US11124500, Example 4 | (2S,3R)-1-[4-[1-(Azetidin-...)
Affinity DataIC50: 11.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518423(US11124500, Example 17 | 6-[1-(Azetidin-3-yl)pyraz...)
Affinity DataIC50: 13.2nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518441(US11124500, Example 32 | 1-[(2S,5R)-2,5-Dimethylpi...)
Affinity DataIC50: 13.3nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518433(US11124500, Example 25 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 13.6nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518410(US11124500, Example 4 | (2S,3R)-1-[4-[1-(Azetidin-...)
Affinity DataIC50: 14.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518412(US11124500, Example 6 | 2-[(2R)-2-(Hydroxymethyl)a...)
Affinity DataIC50: 15.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518419(US11124500, Example 13 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 15.5nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518420(US11124500, Example 14 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 15.9nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518423(US11124500, Example 17 | 6-[1-(Azetidin-3-yl)pyraz...)
Affinity DataIC50: 16.1nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518433(US11124500, Example 25 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 16.9nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518413(US11124500, Example 7 | 2-[(2S,3R)-3-Hydroxy-2-met...)
Affinity DataIC50: 18.1nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518420(US11124500, Example 14 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 19.1nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518406(US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...)
Affinity DataIC50: 20.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518434(US11124500, Example 26 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 22.2nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518406(US11124500, Example 1 | 2-[4-[2-[(2S)-2-Methylazet...)
Affinity DataIC50: 24.2nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518429(US11124500, Example 23 | 6-[1-[2-[(3S,4S)-3,4- Dih...)
Affinity DataIC50: 24.9nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518414(US11124500, Example 8 | 2-[(2S)-2-Methylazetidin-1...)
Affinity DataIC50: 25.2nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518412(US11124500, Example 6 | 2-[(2R)-2-(Hydroxymethyl)a...)
Affinity DataIC50: 25.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518421(US11124500, Example 15 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 26.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518421(US11124500, Example 15 | (2S,3R)-2-Methyl-1-[4-[1-...)
Affinity DataIC50: 27.2nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518422(US11124500, Example 16 | [(2R)-1-[4-[1-[(3R)-Pyrro...)
Affinity DataIC50: 28nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518434(US11124500, Example 26 | 2-[(2S)-2-Methylazetidin-...)
Affinity DataIC50: 28.4nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518425(US11124500, Example 19 | 6-[1-(1-Acetyl-4-piperidy...)
Affinity DataIC50: 29.2nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518422(US11124500, Example 16 | [(2R)-1-[4-[1-[(3R)-Pyrro...)
Affinity DataIC50: 30nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Eli Lilly

US Patent
LigandPNGBDBM518428(US11124500, Example 22 | 6-[1-[2-[(3R,4R)-3,4- Dih...)
Affinity DataIC50: 33.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetKetohexokinase(Human)
Eli Lilly

US Patent
LigandPNGBDBM518439(US11124500, Example 31 | 1-(3,3-Dimethylpiperazin-...)
Affinity DataIC50: 34.7nMAssay Description:The intrinsic potency for inhibition of KHK C or A activity may be measured using an enzymatic assay which measures the production of FIP. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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