Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 10189
TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518793(US11117898, Example 6 | 6-Butoxy-1-(3-(piperidin-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518790(US11117898, Example 3 | 6-Butoxy-1-(4-(piperidin-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518783(US11117898, Example 1 | 6-Butoxy-1-(4-(pyrrolidin-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518790(US11117898, Example 3 | 6-Butoxy-1-(4-(piperidin-1...)
Affinity DataIC50: 4.00E+3nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518792(US11117898, Example 4 | 6-Butoxy-1-(3-(pyrrolidin-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518790(US11117898, Example 3 | 6-Butoxy-1-(4-(piperidin-1...)
Affinity DataIC50: 7.00E+3nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518789(US11117898, Example 2 | 1-(4-(Azetidin-1-ylmethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518793(US11117898, Example 6 | 6-Butoxy-1-(3-(piperidin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518793(US11117898, Example 6 | 6-Butoxy-1-(3-(piperidin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518792(US11117898, Example 4 | 6-Butoxy-1-(3-(pyrrolidin-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518783(US11117898, Example 1 | 6-Butoxy-1-(4-(pyrrolidin-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518792(US11117898, Example 4 | 6-Butoxy-1-(3-(pyrrolidin-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518796(US11117898, Example 12 | 1-(4-Amino-1-(4-pyrrolidi...)
Affinity DataIC50: 1.60E+4nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518796(US11117898, Example 12 | 1-(4-Amino-1-(4-pyrrolidi...)
Affinity DataIC50: 1.60E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518789(US11117898, Example 2 | 1-(4-(Azetidin-1-ylmethyl)...)
Affinity DataIC50: 1.90E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518794(US11117898, Example 7 | 6-(2-Methoxyethoxy)-1-(4-(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518789(US11117898, Example 2 | 1-(4-(Azetidin-1-ylmethyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518783(US11117898, Example 1 | 6-Butoxy-1-(4-(pyrrolidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Example 5: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518794(US11117898, Example 7 | 6-(2-Methoxyethoxy)-1-(4-(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518794(US11117898, Example 7 | 6-(2-Methoxyethoxy)-1-(4-(...)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM518796(US11117898, Example 12 | 1-(4-Amino-1-(4-pyrrolidi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Test Example 4: 100 mM PBS buffer was formulated, which was then used to formulate 2.5 mg/ml microsome solution and 5 mM NADPH solution. The 5× conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent