Compile Data Set for Download or QSAR
Report error Found 111 Enz. Inhib. hit(s) with all data for entry = 10160
TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515339(US11110088, Compound Table 1.13)
Affinity DataIC50: 1.5nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515327(US11110088, Compound Table 1.1)
Affinity DataIC50: 1.60nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515333(US11110088, Compound Table 1.7)
Affinity DataIC50: 1.60nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515342(US11110088, Compound Table 1.16)
Affinity DataIC50: 1.60nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515334(US11110088, Compound Table 1.8)
Affinity DataIC50: 1.70nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515335(US11110088, Compound Table 1.9)
Affinity DataIC50: 1.80nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515340(US11110088, Compound Table 1.14)
Affinity DataIC50: 1.80nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515340(US11110088, Compound Table 1.14)
Affinity DataIC50: 1.80nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515334(US11110088, Compound Table 1.8)
Affinity DataIC50: 1.90nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515334(US11110088, Compound Table 1.8)
Affinity DataIC50: 1.90nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515339(US11110088, Compound Table 1.13)
Affinity DataIC50: 1.90nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515340(US11110088, Compound Table 1.14)
Affinity DataIC50: 1.90nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515327(US11110088, Compound Table 1.1)
Affinity DataIC50: 2nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515329(US11110088, Compound Table 1.3)
Affinity DataIC50: 2nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515333(US11110088, Compound Table 1.7)
Affinity DataIC50: 2nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515333(US11110088, Compound Table 1.7)
Affinity DataIC50: 2.10nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515336(US11110088, Compound Table 1.10)
Affinity DataIC50: 2.10nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515327(US11110088, Compound Table 1.1)
Affinity DataIC50: 2.20nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515341(US11110088, Compound Table 1.15)
Affinity DataIC50: 2.20nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515334(US11110088, Compound Table 1.8)
Affinity DataIC50: 2.40nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515339(US11110088, Compound Table 1.13)
Affinity DataIC50: 2.40nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515328(US11110088, Compound Table 1.2)
Affinity DataIC50: 2.5nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515329(US11110088, Compound Table 1.3)
Affinity DataIC50: 2.5nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515340(US11110088, Compound Table 1.14)
Affinity DataIC50: 2.60nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515342(US11110088, Compound Table 1.16)
Affinity DataIC50: 2.70nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515333(US11110088, Compound Table 1.7)
Affinity DataIC50: 2.90nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515339(US11110088, Compound Table 1.13)
Affinity DataIC50: 2.90nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515329(US11110088, Compound Table 1.3)
Affinity DataIC50: 3nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515342(US11110088, Compound Table 1.16)
Affinity DataIC50: 3nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515327(US11110088, Compound Table 1.1)
Affinity DataIC50: 3.10nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515335(US11110088, Compound Table 1.9)
Affinity DataIC50: 3.10nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515341(US11110088, Compound Table 1.15)
Affinity DataIC50: 3.40nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515341(US11110088, Compound Table 1.15)
Affinity DataIC50: 3.5nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515343(US11110088, Compound Table 1.17)
Affinity DataIC50: 3.5nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515336(US11110088, Compound Table 1.10)
Affinity DataIC50: 3.70nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515332(US11110088, Compound Table 1.6)
Affinity DataIC50: 3.80nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515338(US11110088, Compound Table 1.12)
Affinity DataIC50: 3.80nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515328(US11110088, Compound Table 1.2)
Affinity DataIC50: 3.90nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515330(US11110088, Compound Table 1.4)
Affinity DataIC50: 3.90nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515335(US11110088, Compound Table 1.9)
Affinity DataIC50: 3.90nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515342(US11110088, Compound Table 1.16)
Affinity DataIC50: 3.90nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515329(US11110088, Compound Table 1.3)
Affinity DataIC50: 4.20nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515331(US11110088, Compound Table 1.11 | US11110088, Comp...)
Affinity DataIC50: 4.20nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515331(US11110088, Compound Table 1.11 | US11110088, Comp...)
Affinity DataIC50: 4.5nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515335(US11110088, Compound Table 1.9)
Affinity DataIC50: 4.5nMAssay Description:BMX enzyme (Millipore #14-499M), is diluted to 0.5 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515331(US11110088, Compound Table 1.11 | US11110088, Comp...)
Affinity DataIC50: 4.60nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515341(US11110088, Compound Table 1.15)
Affinity DataIC50: 4.70nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Tec(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515336(US11110088, Compound Table 1.10)
Affinity DataIC50: 5nMAssay Description:TEC enzyme (Millipore #14-801M), is diluted to 2 U/mL in KR buffer (10 mM Tris-HCl, 10 mM MgCl2, 0.01% Tween-20, 0.1% NaN3, 1 mM DTT, 2 mM MnCl2, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515331(US11110088, Compound Table 1.11 | US11110088, Comp...)
Affinity DataIC50: 5.10nMAssay Description:BTK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.BTK enzyme (H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase TXK(Human)
Acerta Pharma

US Patent
LigandPNGBDBM515331(US11110088, Compound Table 1.11 | US11110088, Comp...)
Affinity DataIC50: 5.10nMAssay Description:TXK enzyme activity is measured using the IMAP (immobilized metal ion affinity-based fluorescence polarization) assay as outlined below.TXK enzyme (M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
Go to US Patent

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