Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 10109
TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514198(US11053196, Compound 5A)
Affinity DataEC50:  2.30nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514210(US11053196, Compound 11 | 4-(3-((1-(4-chlorophenyl...)
Affinity DataEC50:  0.280nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514209(US11053196, Compound 10B)
Affinity DataEC50:  37nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514208(US11053196, Compound 10A)
Affinity DataEC50:  0.300nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514207(US11053196, Compound 10 | 4-(3-((1-(4-chlorophenyl...)
Affinity DataEC50:  0.520nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514206(US11053196, Compound 9 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.990nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514205(US11053196, Compound 8 | 4-(3-((1-(4-chloro-2-(2-h...)
Affinity DataEC50:  0.150nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514204(US11053196, Compound 7B-D)
Affinity DataEC50:  16nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514203(US11053196, Compound 7A-D)
Affinity DataEC50:  0.100nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514202(US11053196, Compound 6B)
Affinity DataEC50:  0.390nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514201(US11053196, Compound 6A)
Affinity DataEC50:  250nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514200(US11053196, Compound 6 | 4-(3-((1-(4-fluoro-2-meth...)
Affinity DataEC50:  0.630nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514199(US11053196, Compound 5B)
Affinity DataEC50:  0.120nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514142(US11053196, Compound 1 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.640nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514197(US11053196, Compound 5 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.110nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514196(US11053196, Compound 4B)
Affinity DataEC50:  0.0570nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514195(US11053196, Compound 4A)
Affinity DataEC50:  11nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514194(US11053196, Compound 4 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.110nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514183(US11053196, Compound 3B)
Affinity DataEC50:  0.120nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514179(US11053196, Compound 3A)
Affinity DataEC50:  36nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514178(US11053196, Compound 3 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.560nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514148(US11053196, Compound 2B)
Affinity DataEC50:  0.0780nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514147(US11053196, Compound 2A)
Affinity DataEC50:  15nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514146(US11053196, Compound 2 | 4-(3-((1-(4-chlorophenyl)...)
Affinity DataEC50:  0.380nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514145(US11053196, Compound 1B)
Affinity DataEC50:  0.110nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetGenome polyprotein(DENV-2)
Janssen Pharmaceuticals

US Patent
LigandPNGBDBM514144(US11053196, Compound 1A)
Affinity DataEC50:  1.30nMAssay Description:The antiviral activity of all the compounds of the invention was tested against the DENV-2 16681 strain which was labeled with enhanced green fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent