Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 9853
TargetAndrogen receptor(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM493530(US10981926, Cpd No. 43 | 5-[5-oxo-8-[6-(4-piperidy...)
Affinity DataIC50: 6.90nMAssay Description:ReceptorsGR (human) (agonist radioligand) IM-9 cells (cytosol)[3H]dexamethasone 1.5 nM 1.5 nM triamcinolone (10 μM) 6 h 4° C. Scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
Go to US Patent

TargetGlucocorticoid receptor(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM493530(US10981926, Cpd No. 43 | 5-[5-oxo-8-[6-(4-piperidy...)
Affinity DataIC50: 3.00E+4nMAssay Description:ReceptorsGR (human) (agonist radioligand) IM-9 cells (cytosol)[3H]dexamethasone 1.5 nM 1.5 nM triamcinolone (10 μM) 6 h 4° C. Scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM493530(US10981926, Cpd No. 43 | 5-[5-oxo-8-[6-(4-piperidy...)
Affinity DataKi:  3nMAssay Description:ReceptorsGR (human) (agonist radioligand) IM-9 cells (cytosol)[3H]dexamethasone 1.5 nM 1.5 nM triamcinolone (10 μM) 6 h 4° C. Scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
Go to US Patent