Compile Data Set for Download or QSAR
Report error Found 185 Enz. Inhib. hit(s) with all data for entry = 9831
TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492438(US10975084, Example 11-145 | 5-(1-tert-butyl-1H- p...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492449(US10975084, Example 11-12 | 6-(1-methylethyl)-5-[1...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492450(US10975084, Example 11-13 | 5-{1-[(1- fluorocyclop...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492451(US10975084, Example 11-14 | 5-[1- (cyclopropylmeth...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492457(US10975084, Example 11-20 | 6-(1-methylethyl)-5-[1...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492458(US10975084, Example 11-21 | 6-(1-methylethyl)-5-(1...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492544(US10975084, Example 11-107 | 5-[1-(2-hydroxy-1,1- ...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492545(US10975084, Example 11-108 | 6-(1-methylethyl)-5-[...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492546(US10975084, Example 11-109 | 5-(1-cyclobutyl-1H- p...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492571(US10975084, Example 11-134 | 5-(1-tert-butyl-1H-py...)
Affinity DataIC50: 5.08nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492439(US10975084, Example 11-146 | 5-[1-(3-methylbutyl)-...)
Affinity DataIC50: 5.22nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492529(US10975084, Example 11-92 | 5-[1-(2-methoxy-1,1- d...)
Affinity DataIC50: 5.29nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492453(US10975084, Example 11-16 | 5-[1-(2-methoxyethyl)-...)
Affinity DataIC50: 5.73nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492455(US10975084, Example 11-18 | 5-(1-cyclopropyl-1H- p...)
Affinity DataIC50: 5.74nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492477(US10975084, Example 11-40 | 6-(1-methylethyl)-5-[1...)
Affinity DataIC50: 5.77nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492476(US10975084, Example 11-39 | 6-(1-methylethyl)-5-[1...)
Affinity DataIC50: 5.83nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492456(US10975084, Example 11-19 | 5-(1-ethyl-1H-pyrazol-...)
Affinity DataIC50: 6.27nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492445(US10975084, Example 11-8 | 6-(1-methylethyl)-5-(1-...)
Affinity DataIC50: 6.28nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492454(US10975084, Example 11-17 | 5-[1-(4-fluorophenyl)-...)
Affinity DataIC50: 6.47nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492547(US10975084, Example 11-110 | 6-(1-methylethyl)-5-[...)
Affinity DataIC50: 6.70nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492484(US10975084, Example 11-47 | 6-(1-methylethyl)-5-{1...)
Affinity DataIC50: 6.93nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492560(US10975084, Example 11-123 | 6-(1-methylethyl)-5-(...)
Affinity DataIC50: 6.93nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492489(US10975084, Example 11-52 | 6-(1-methylethyl)-5-[1...)
Affinity DataIC50: 6.96nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492527(US10975084, Example 11-90 | 6-(1-methylethyl)-5-[4...)
Affinity DataIC50: 7.26nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492446(US10975084, Example 11-9 | 5-(1-benzyl-1H-pyrazol-...)
Affinity DataIC50: 7.30nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492562(US10975084, Example 11-125 | 6-(1-methylethyl)-5-[...)
Affinity DataIC50: 7.36nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492452(US10975084, Example 11-15 | 6-(1-methylethyl)-5-[1...)
Affinity DataIC50: 7.5nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492447(US10975084, Example 11-10 | 6-(1-methylethyl)-5-(4...)
Affinity DataIC50: 7.52nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492538(US10975084, Example 11-101 | 6-[6-(1-methylethyl)-...)
Affinity DataIC50: 7.57nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492525(US10975084, Example 11-88 | 6-(1-methylethyl)-5-(4...)
Affinity DataIC50: 8.57nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492532(US10975084, Example 11-95 | 6-(1-methylethyl)-5-[4...)
Affinity DataIC50: 8.59nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492561(US10975084, Example 11-124 | N-{4-[6-(1-methylethy...)
Affinity DataIC50: 8.76nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492519(US10975084, Example 11-82 | 6-(1-methylethyl)-5-[4...)
Affinity DataIC50: 8.78nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492503(US10975084, Example 11-66 | {3-[6-(1-methylethyl)-...)
Affinity DataIC50: 8.93nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492492(US10975084, Example 11-55 | 6-(1-methylethyl)-5-[(...)
Affinity DataIC50: 9.45nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492488(US10975084, Example 11-51 | 5-[1-(3-chlorophenyl)-...)
Affinity DataIC50: 9.66nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492555(US10975084, Example 11-118 | 6-(1-methylethyl)-5-(...)
Affinity DataIC50: 9.79nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492515(US10975084, Example 11-78 | 6-(1-methylethyl)-5-(1...)
Affinity DataIC50: 10.4nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492563(US10975084, Example 11-126 | 6-(1-methylethyl)-5-(...)
Affinity DataIC50: 10.4nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492564(US10975084, Example 11-127 | 6-(1-methylethyl)-5-(...)
Affinity DataIC50: 11.6nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492548(US10975084, Example 11-111 | 5-[1-(2-hydroxyethyl)...)
Affinity DataIC50: 11.7nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492478(US10975084, Example 11-41 | 6-(1-methylethyl)-5-(4...)
Affinity DataIC50: 11.8nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492565(US10975084, Example 11-128 | 6-(1-methylethyl)-5-[...)
Affinity DataIC50: 12.3nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492523(US10975084, Example 11-86 | N,N-dimethyl-4-[6-(1- ...)
Affinity DataIC50: 12.6nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492559(US10975084, Example 11-122 | 6-(1-methylethyl)-5-(...)
Affinity DataIC50: 13.3nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492497(US10975084, Example 11-60 | 5-[4-(hydroxymethyl)ph...)
Affinity DataIC50: 13.5nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492507(US10975084, Example 11-70 | 5-(1H-benzimidazol-6-y...)
Affinity DataIC50: 13.5nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492533(US10975084, Example 11-96 | 5-[4-(1,1- dioxidothio...)
Affinity DataIC50: 13.5nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492511(US10975084, Example 11-74 | 6-(1-methylethyl)-5- q...)
Affinity DataIC50: 14.7nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetLysine-specific demethylase 5B(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM492530(US10975084, Example 11-93 | 6-(1-methylethyl)-5-{4...)
Affinity DataIC50: 15.5nMAssay Description:In this assay, the potency (IC50) of each compound was determined from a ten point (1:3 serial dilution; final compound concentration range in assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

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