Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 9823
TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385383(6-(2-((2,6-Dimethylphenyl)amino)-1H-imidazol-1-yl)...)
Affinity DataIC50: 111nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385384(US10287268, Compound I-2 | US10975058, Compound I-...)
Affinity DataIC50: 307nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385383(6-(2-((2,6-Dimethylphenyl)amino)-1H-imidazol-1-yl)...)
Affinity DataIC50: 338nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385384(US10287268, Compound I-2 | US10975058, Compound I-...)
Affinity DataIC50: 1.86E+3nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385385(US10287268, Compound I-3 | US10975058, Compound I-...)
Affinity DataIC50: 2.42E+3nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase HCK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385386(US10287268, Compound I-4 | US10975058, Compound I-...)
Affinity DataIC50: 3.00E+3nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385385(US10287268, Compound I-3 | US10975058, Compound I-...)
Affinity DataIC50: 9.98E+3nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM385386(US10287268, Compound I-4 | US10975058, Compound I-...)
Affinity DataIC50: 1.00E+4nMAssay Description:This buffer consisted of 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 1 mg ml−1 bovine serum albumin and 0.1% (vol/vol) 2-mercaptoethanol.10× Concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
Go to US Patent