Compile Data Set for Download or QSAR
Report error Found 228 Enz. Inhib. hit(s) with all data for entry = 9819
TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490802(US10975037, Example 1 | Step b | 4-Chloro-1-ethyl-...)
Affinity DataKd:  0.600nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490803(US10975037, Example 2 | 4-Chloro-5-(2-(difluoromet...)
Affinity DataKd:  0.160nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490804(US10975037, Example 3 | 4-Chloro-1-ethyl-5-(2-meth...)
Affinity DataKd:  0.630nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490805(US10975037, Example 4 | 5-(2-(difluoromethoxy)-4-(...)
Affinity DataKd:  2nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490806(US10975037, Example 5 | N-(((1RS,2RS,4RS)-2-Amino-...)
Affinity DataKd:  1.70nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490807(US10975037, Example 6 | N-(((1R*,2R*,4R*)-2-Amino-...)
Affinity DataKd:  2.40nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490808(US10975037, Example 7 | N-(((1S*,2S*,4S*)-2-Amino-...)
Affinity DataKd:  2.10nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490809(US10975037, Example 8 | 4-Chloro-5-(2-(difluoromet...)
Affinity DataKd:  0.730nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490810(US10975037, Example 9 | 4-Chloro-5-(2-(difluoromet...)
Affinity DataKd:  1.60nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490811(US10975037, Example 10 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  2.60nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490812(US10975037, Example 11 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  35nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490813(US10975037, Example 12 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  74nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490814(US10975037, Example 13 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  110nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490815(US10975037, Example 14 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.140nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490816(US10975037, Example 15 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.130nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490815(US10975037, Example 14 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.190nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490818(US10975037, Example 17 | 4-Chloro-1-ethyl-5-(2-met...)
Affinity DataKd:  1.30E+3nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490819(US10975037, Example 18 | 4-Chloro-1-ethyl-5-(2-met...)
Affinity DataKd:  240nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490820(US10975037, Example 19 | N-(((1s*,4s*)-1-Amino-4-(...)
Affinity DataKd:  2.20nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490820(US10975037, Example 19 | N-(((1s*,4s*)-1-Amino-4-(...)
Affinity DataKd:  95nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490822(US10975037, Example 21 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.370nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490823(US10975037, Example 22 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.440nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490824(US10975037, Example 23 | 4-Chloro-1-ethyl-5-(2-met...)
Affinity DataKd:  4.60nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490825(US10975037, Example 24 | 4-Chloro-1-ethyl-N-(((1s,...)
Affinity DataKd:  21nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490827(US10975037, Example 25 | 4-Chloro-1-ethyl-5-(2-met...)
Affinity DataKd:  31nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490828(US10975037, Example 26 | 1-(tert-Butyl)-4-chloro-5...)
Affinity DataKd:  3.90nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490829(US10975037, Example 27 | 1-(tert-Butyl)-4-chloro-N...)
Affinity DataKd:  7.40nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490830(US10975037, Example 28 | 4-Chloro-1-isobutyl-5-(2-...)
Affinity DataKd:  2.5nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490831(US10975037, Example 29 | 4-Chloro-N-(((1s,4S)-1-hy...)
Affinity DataKd:  8.30nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490832(US10975037, Example 30 | 4-Chloro-5-(2-methoxy-4-(...)
Affinity DataKd:  2.10nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490833(US10975037, Example 31 | 4-Chloro-N-(((1s,4S)-1-hy...)
Affinity DataKd:  7.20nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490834(US10975037, Example 32 | 4-Chloro-N-(((1s,4S)-1-cy...)
Affinity DataKd:  7.60nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490835(US10975037, Example 33 | 4-Chloro-N-(((1r,4R)-1-cy...)
Affinity DataKd:  450nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490836(US10975037, Example 34 | N-(((1r,4R)-1-carbamoyl-4...)
Affinity DataKd:  3.00E+3nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490837(US10975037, Example 35 | N-(((1s,4S)-1-carbamoyl-4...)
Affinity DataKd:  34nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490838(US10975037, Example 36 | 4-Chloro-1-ethyl-N-(((1s,...)
Affinity DataKd:  1nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490839(US10975037, Example 37 | 4-Chloro-1-ethyl-N-(((1s,...)
Affinity DataKd:  2nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490840(US10975037, Example 38 | 4-Chloro-1-ethyl-5-(2-met...)
Affinity DataKd:  3.30nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490841(US10975037, Example 39 | 4-Chloro-1-ethyl-N-(((1s,...)
Affinity DataKd:  10nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490842(US10975037, Example 40 | 4-Chloro-N-(((1s,4R)-1-hy...)
Affinity DataKd:  0.710nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490843(US10975037, Example 41 | 4-Chloro-5-(2-methoxy-4-(...)
Affinity DataKd:  0.280nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490844(US10975037, Example 42 | 4-Chloro-N-(((1s,4S)-1-hy...)
Affinity DataKd:  0.420nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490845(US10975037, Example 43 | 4-Chloro-5-(2-methoxy-4-(...)
Affinity DataKd:  0.210nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490846(US10975037, Example 44 | 4-Chloro-1-ethyl-5-(2-met...)
Affinity DataKd:  0.330nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490848(US10975037, Example 45 | 4-Chloro-1-ethyl-N-(((1s,...)
Affinity DataKd:  0.570nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490849(US10975037, Example 46 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.420nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490850(US10975037, Example 47 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.370nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490851(US10975037, Example 48 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  31nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490852(US10975037, Example 49 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  26nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM490853(US10975037, Example 50 | 4-Chloro-5-(2-(difluorome...)
Affinity DataKd:  0.100nMAssay Description:ThermoFluor experiments were carried out using instruments owned by Janssen Research and Development, L.L.C. through its acquisition of 3-Dimensional...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2021
Entry Details
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