Compile Data Set for Download or QSAR
Report error Found 176 Enz. Inhib. hit(s) with all data for entry = 9754
TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429600(US10550091, No. LC-9 | US10947203, No. LC-9)
Affinity DataEC50:  840nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429601(US10550091, No. LC-10 | US10947203, No. LC-10)
Affinity DataEC50:  750nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429602(US10550091, No. LC-11 | US10947203, No. LC-11)
Affinity DataEC50:  880nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429603(US10550091, No. LC-12 | US10947203, No. LC-12)
Affinity DataEC50:  780nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429604(US10550091, No. LC-13 | US10947203, No. LC-13)
Affinity DataEC50:  840nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429605(US10550091, No. LC-14 | US10947203, No. LC-14)
Affinity DataEC50:  7.20E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429606(US10550091, No. LC-15 | US10947203, No. LC-15)
Affinity DataEC50:  3.80E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429607(US10550091, No. LC-16 | US10947203, No. LC-16)
Affinity DataEC50:  1.20E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429608(US10550091, No. LC-17 | US10947203, No. LC-17)
Affinity DataEC50:  1.30E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429611(US10550091, No. LC-20 | US10947203, No. LC-20)
Affinity DataEC50:  910nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429613(US10550091, No. LC-22 | US10947203, No. LC-22)
Affinity DataEC50:  750nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429614(US10550091, No. LC-23 | US10947203, No. LC-23)
Affinity DataEC50:  730nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429615(US10550091, No. LC-24 | US10947203, No. LC-24)
Affinity DataEC50:  880nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429616(US10550091, No. LC-25 | US10947203, No. LC-25)
Affinity DataEC50:  1.70E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429617(US10550091, No. LC-26 | US10947203, No. LC-26)
Affinity DataEC50:  160nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429618(US10550091, No. LC-27 | US10947203, No. LC-27)
Affinity DataEC50:  1.90E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429620(US10550091, No. LC-29 | US10947203, No. LC-29)
Affinity DataEC50:  530nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429622(US10550091, No. LC-31 | US10947203, No. LC-31)
Affinity DataEC50:  760nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429623(US10550091, No. LC-32 | US10947203, No. LC-32)
Affinity DataEC50:  3.40E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429624(US10550091, No. LC-33 | US10947203, No. LC-33)
Affinity DataEC50:  1.20E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429625(US10550091, No. LC-34 | US10947203, No. LC-34)
Affinity DataEC50:  1.60E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429626(US10550091, No. LC-35 | US10947203, No. LC-35)
Affinity DataEC50:  1.30E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429627(US10550091, No. LC-36 | US10947203, No. LC-36)
Affinity DataEC50:  2.40E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429628(US10550091, No. LC-37 | US10947203, No. LC-37)
Affinity DataEC50:  4.10E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429629(US10550091, No. LC-38 | US10947203, No. LC-38)
Affinity DataEC50:  1.30E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429630(US10550091, No. LC-39 | US10947203, No. LC-39)
Affinity DataEC50:  1.00E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429634(US10550091, No. LC-43 | US10947203, No. LC-43)
Affinity DataEC50:  1.50E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429635(US10550091, No. LC-44 | US10947203, No. LC-44)
Affinity DataEC50:  1.20E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429636(US10550091, No. LC-45 | US10947203, No. LC-45)
Affinity DataEC50:  1.10E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429637(US10550091, No. LC-46 | US10947203, No. LC-46)
Affinity DataEC50:  980nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429638(US10550091, No. LC-47 | US10947203, No. LC-47)
Affinity DataEC50:  730nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429639(US10550091, No. LC-48 | US10947203, No. LC-48)
Affinity DataEC50:  700nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429641(US10550091, No. LC-50 | US10947203, No. LC-50)
Affinity DataEC50:  180nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429642(US10550091, No. LC-51 | US10947203, No. LC-51)
Affinity DataEC50:  140nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429645(US10550091, No. LC-54 | US10947203, No. LC-54)
Affinity DataEC50:  530nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429656(US10550091, No. LC-65 | US10947203, No. LC-65)
Affinity DataEC50:  6.10E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429658(US10550091, No. LC-67 | US10947203, No. LC-67)
Affinity DataEC50:  1.70E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429659(US10550091, No. LC-68 | US10947203, No. LC-68)
Affinity DataEC50:  1.50E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429660(US10550091, No. LC-69 | US10947203, No. LC-69)
Affinity DataEC50:  610nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429666(US10550091, No. LC-75 | US10947203, No. LC-75)
Affinity DataEC50:  920nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429667(US10550091, No. LC-76 | US10947203, No. LC-76)
Affinity DataEC50:  2.80E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429668(US10550091, No. LC-77 | US10947203, No. LC-77)
Affinity DataEC50:  790nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429669(US10550091, No. LC-78 | US10947203, No. LC-78)
Affinity DataEC50:  1.40E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429671(US10550091, No. LC-80 | US10947203, No. LC-80)
Affinity DataEC50:  2.40E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429672(US10550091, No. LC-81 | US10947203, No. LC-81)
Affinity DataEC50:  1.20E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429674(US10550091, No. LC-83 | US10947203, No. LC-83)
Affinity DataEC50:  5.00E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429675(US10550091, No. LC-84 | US10947203, No. LC-84)
Affinity DataEC50:  3.30E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429678(US10550091, No. LC-87 | US10947203, No. LC-87)
Affinity DataEC50:  1.20E+4nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429673(US10550091, No. LC-82 | US10550091, No. LC-88 | US...)
Affinity DataEC50:  1.40E+3nMAssay Description:The hPXR transactivation assays (PXR agonistic and antagonistic assays) were performed in the HepG2 cells stably expressing FLAG-hPXR and CYP3A4-luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetNuclear receptor subfamily 1 group I member 2(Human)
St. Jude Children''S Rsearch Hospital

US Patent
LigandPNGBDBM429599(US10550091, No. LC-8 | US10947203, No. LC-8)
Affinity DataIC50: 10nMAssay Description:The time-resolved fluorescence resonance transfer (TR-FRET) hPXR competitive binding assay was performed according to the manufacturer's instruct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

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