Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 9749
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 120nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 150nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 200nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Dog)
Pfizer

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 200nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 210nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 410nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Dog)
Pfizer

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 590nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Pfizer

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 730nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Pfizer

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 1.50E+3nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 1.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Pfizer

US Patent
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTryptophan 2,3-dioxygenase(Mouse)
Pfizer

US Patent
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 2,3-dioxygenase(Mouse)
Pfizer

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTryptophan 2,3-dioxygenase(Mouse)
Pfizer

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM310197(US9603836, Compound 2a | US9949951, 2a | US1094599...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM310195(US9603836, Compound 2 | (-)-(R)-3-(5-fluoro-1H- in...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent

TargetTryptophan 2,3-dioxygenase(Human)
Pfizer

US Patent
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:To measure enzymatic activity of human IDO1, the reaction mixture contained (final concentrations) potassium phosphate buffer (50 mM, pH 6.5), ascorb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent