Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 9748
TargetOxysterols receptor LXR-alpha(Human)
Rockefeller University

US Patent
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  200nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Rockefeller University

US Patent
LigandPNGBDBM19992(2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...)
Affinity DataEC50:  40nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Rockefeller University

US Patent
LigandPNGBDBM426493(US10669296, Compound SB742881 | US10543183, Compou...)
Affinity DataEC50:  74nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Rockefeller University

US Patent
LigandPNGBDBM426493(US10669296, Compound SB742881 | US10543183, Compou...)
Affinity DataEC50:  25nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Rockefeller University

US Patent
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  20nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-beta(Human)
Rockefeller University

US Patent
LigandPNGBDBM19993(CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...)
Affinity DataEC50:  50nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Rockefeller University

US Patent
LigandPNGBDBM26066(JMC517161 Compound 12 | 2-[(2-chloro-4-fluoropheny...)
Affinity DataEC50:  179nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Rockefeller University

US Patent
LigandPNGBDBM26066(JMC517161 Compound 12 | 2-[(2-chloro-4-fluoropheny...)
Affinity DataEC50:  24nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetOxysterols receptor LXR-alpha(Human)
Rockefeller University

US Patent
LigandPNGBDBM50204072(CHEMBL3945199 | US10543183, Compound 12 | US109459...)
Affinity DataEC50: <100nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Rockefeller University

US Patent
LigandPNGBDBM50204072(CHEMBL3945199 | US10543183, Compound 12 | US109459...)
Affinity DataEC50:  11nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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PDB3D3D Structure (crystal)
TargetOxysterols receptor LXR-alpha(Human)
Rockefeller University

US Patent
LigandPNGBDBM50034775(CHEMBL3360975 | US10543183, Compound 38 | US109459...)
Affinity DataEC50:  550nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
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TargetOxysterols receptor LXR-beta(Human)
Rockefeller University

US Patent
LigandPNGBDBM50034775(CHEMBL3360975 | US10543183, Compound 38 | US109459...)
Affinity DataEC50:  630nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
Go to US Patent