Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 9730
TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484440(US10934285, Example 24 | US12053470, Compound 47)
Affinity DataIC50: 1nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484457(US10934285, Example 43)
Affinity DataIC50: 1.5nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484469(US10934285, Example 55)
Affinity DataIC50: 2.80nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484421(US10934285, Example 5)
Affinity DataIC50: 3nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484472(US10934285, Example 59)
Affinity DataIC50: 3nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484466(US10934285, Example 52)
Affinity DataIC50: 3nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484461(US10934285, Example 47)
Affinity DataIC50: 3nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484467(US10934285, Example 53 | US12053470, Compound 46)
Affinity DataIC50: 4.40nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484429(US10934285, Example 13 | US12053470, Compound 52)
Affinity DataIC50: 4.60nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484439(US10934285, Example 23)
Affinity DataIC50: 5nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484422(US10934285, Example 6)
Affinity DataIC50: 5nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484430(US10934285, Example 14 | US12053470, Compound 51)
Affinity DataIC50: 5.90nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484419(US10934285, Example 3)
Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484451(US10934285, Example 37)
Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484426(US10934285, Example 10)
Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484423(US10934285, Example 7 | US12053470, Compound 48)
Affinity DataIC50: 6nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484470(US10934285, Example 56)
Affinity DataIC50: 6.60nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484459(US10934285, Example 45)
Affinity DataIC50: 7nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484418(US10934285, Example 2 | US12053470, Compound 50)
Affinity DataIC50: 7nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484425(US10934285, Example 9)
Affinity DataIC50: 7nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484468(US10934285, Example 54 | US12053470, Compound 54)
Affinity DataIC50: 7.30nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484432(US10934285, Example 16)
Affinity DataIC50: 8nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484446(US10934285, Example 32)
Affinity DataIC50: 8nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484438(US10934285, Example 22)
Affinity DataIC50: 10nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484431(US10934285, Example 15)
Affinity DataIC50: 10nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484447(US10934285, Example 33)
Affinity DataIC50: 10nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484471(US10934285, Example 57)
Affinity DataIC50: 11nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484473(US10934285, Example 60)
Affinity DataIC50: 11nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484455(US10934285, Example 41)
Affinity DataIC50: 11nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484465(US10934285, Example 51)
Affinity DataIC50: 12nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484443(US10934285, Example 29)
Affinity DataIC50: 12nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484450(US10934285, Example 36)
Affinity DataIC50: 12nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484427(US10934285, Example 11)
Affinity DataIC50: 12nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484433(US10934285, Example 17)
Affinity DataIC50: 13nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484453(US10934285, Example 39)
Affinity DataIC50: 13nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484448(US10934285, Example 34)
Affinity DataIC50: 14nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484458(US10934285, Example 44)
Affinity DataIC50: 14nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484452(US10934285, Example 38)
Affinity DataIC50: 15nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484456(US10934285, Example 42)
Affinity DataIC50: 16nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484444(US10934285, Example 30)
Affinity DataIC50: 16nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484474(US10934285, Example 61)
Affinity DataIC50: 22nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484441(N-(3-((3-Amino-5-((3S,4S)-4-amino-3-methyl-2-oxa-8...)
Affinity DataIC50: 23nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484475(US10934285, Example 62)
Affinity DataIC50: 25nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484449(US10934285, Example 35)
Affinity DataIC50: 35nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484463(US10934285, Example 49)
Affinity DataIC50: 36nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
Go to US Patent

TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484445(US10934285, Example 31)
Affinity DataIC50: 38nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484478(US10934285, Example 65)
Affinity DataIC50: 42nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484442(US10934285, Example 28 | US12053470, Compound 49)
Affinity DataIC50: 42nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484424(US10934285, Example 8)
Affinity DataIC50: 44nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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TargetSH2B adapter protein 2(Human)
Novartis

US Patent
LigandPNGBDBM484476(US10934285, Example 63)
Affinity DataIC50: 52nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.003-100 μM) was monitored using an assay in which 0.5 nM of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
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