Compile Data Set for Download or QSAR
Report error Found 518 Enz. Inhib. hit(s) with all data for entry = 9559
TargetAdenosine receptor A2b(Human)
TBA

US Patent
LigandPNGBDBM474223(2-(2,6-difluorobenzyl)-8-(2-(dimethylamino) pyridi...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM474233(5-[5-amino-7-(4-fluorophenyl)-2-[(3-fluoropyrid in...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474284(US10858365, Compound 69 | 7-(4-fluorophenyl)-2-((3...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474287(US10858365, Compound 73 | 2-((3-(difluoromethoxy)p...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474315(US10858365, Compound 105-1 | 7-(4-fluorophenyl)-8-...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474316(US10858365, Compound 105-2 | 7-(4-fluorophenyl)-8-...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474337(US10858365, Compound 124 | 7-(azetidin-l-yl)-2-(2,...)
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474223(2-(2,6-difluorobenzyl)-8-(2-(dimethylamino) pyridi...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474281(7-(4-fluorophenyl)-2-((3-fluoropyridin-2-yl) methy...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474318(US10858365, Compound 106-2 | 8-(3-methylimidazo[l,...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474328(US10858365, Compound 114 | 7-(4-fluorophenyl)-2-(2...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474329(US10858365, Compound 116 | 7-(3-fluoro-1H-pyrazol-...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474329(US10858365, Compound 116 | 7-(3-fluoro-1H-pyrazol-...)
Affinity DataIC50: 0.200nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474330(US10858365, Compound 117 | 7-(4-fluoro-1H-pyrazol-...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474334(US10858365, Compound 121 | 2-(2,6-difluorobenzyl)-...)
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474284(US10858365, Compound 69 | 7-(4-fluorophenyl)-2-((3...)
Affinity DataIC50: 0.300nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474335(US10858365, Compound 122 | (S)-7-(4-fluorophenyl)-...)
Affinity DataIC50: 0.300nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
TBA

US Patent
LigandPNGBDBM474230(5-(5-amino-7-(4-fluorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50: 0.400nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474223(2-(2,6-difluorobenzyl)-8-(2-(dimethylamino) pyridi...)
Affinity DataIC50: 0.400nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474287(US10858365, Compound 73 | 2-((3-(difluoromethoxy)p...)
Affinity DataIC50: 0.400nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474300(US10858365, Compound 89 | 7-(4-fluorophenyl)-2-((3...)
Affinity DataIC50: 0.400nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474328(US10858365, Compound 114 | 7-(4-fluorophenyl)-2-(2...)
Affinity DataIC50: 0.400nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474336(US10858365, Compound 123 | 2-(2,6-difluorobenzyl)-...)
Affinity DataIC50: 0.400nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474338(US10858365, Compound 125 | (R)-7-(4-fluorophenyl)-...)
Affinity DataIC50: 0.400nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474309(US10858365, Compound 99 | 2-((3-fluoropyridin-2-yl...)
Affinity DataIC50: 0.5nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474317(US10858365, Compound 106-1 | 8-(3-methyiimidazo[l,...)
Affinity DataIC50: 0.5nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474319(US10858365, Compound 107-1 | 8-(3-methylimidazo[l,...)
Affinity DataIC50: 0.5nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474320(US10858365, Compound 107-2 | 8-(3-methylimidazo[l,...)
Affinity DataIC50: 0.5nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474330(US10858365, Compound 117 | 7-(4-fluoro-1H-pyrazol-...)
Affinity DataIC50: 0.5nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50: 0.600nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474281(7-(4-fluorophenyl)-2-((3-fluoropyridin-2-yl) methy...)
Affinity DataIC50: 0.600nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474333(US10858365, Compound 120 | 2-(2-(dimethylamino)eth...)
Affinity DataIC50: 0.600nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474233(5-[5-amino-7-(4-fluorophenyl)-2-[(3-fluoropyrid in...)
Affinity DataIC50: 0.700nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474292(US10858365, Compound 79 | 5-(5-am i no-2-(2,6-difl...)
Affinity DataIC50: 0.700nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474299(US10858365, Compound 88 | 8-(benzo[d]thiazol-6-yl)...)
Affinity DataIC50: 0.700nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM474230(5-(5-amino-7-(4-fluorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50: 0.800nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM474237(5-(5-amino-7-(3-chlorophenyl)-2-((3-fluoropyrid in...)
Affinity DataIC50: 0.800nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50: 0.800nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474233(5-[5-amino-7-(4-fluorophenyl)-2-[(3-fluoropyrid in...)
Affinity DataIC50: 0.800nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474288(US10858365, Compound 74 | 2-((3-(difluoromethoxy)p...)
Affinity DataIC50: 0.800nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474309(US10858365, Compound 99 | 2-((3-fluoropyridin-2-yl...)
Affinity DataIC50: 0.800nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474223(2-(2,6-difluorobenzyl)-8-(2-(dimethylamino) pyridi...)
Affinity DataIC50: 0.900nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474229(7-(4-fluorophenyl)-2-((3-fluoropyridin-2-yl) methy...)
Affinity DataIC50: 0.900nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474292(US10858365, Compound 79 | 5-(5-am i no-2-(2,6-difl...)
Affinity DataIC50: 0.900nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474314(US10858365, Compound 104 | (R)-7-(4-fluorophenyl)-...)
Affinity DataIC50: 1nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474315(US10858365, Compound 105-1 | 7-(4-fluorophenyl)-8-...)
Affinity DataIC50: 1nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Mouse)
TBA

US Patent
LigandPNGBDBM474316(US10858365, Compound 105-2 | 7-(4-fluorophenyl)-8-...)
Affinity DataIC50: 1nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
TBA

US Patent
LigandPNGBDBM474221(8-(2,6-dimethylpyridin-4-yl)-7-(4-fluoropheny1)- 2...)
Affinity DataIC50: 1.10nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
TBA

US Patent
LigandPNGBDBM474339(US10858365, Compound 126 | 2-(2-methoxyethyl)-8-(3...)
Affinity DataIC50: 1.10nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

Displayed 1 to 50 (of 518 total ) | Next | Last >>
Jump to: