Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 9550
TargetHistone deacetylase 6(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US8614223, 73 | US10858323, Compound 1)
Affinity DataIC50: 1.70nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetHistone deacetylase 6(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50: 2nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 10nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 58nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 64nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50: 68nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50: 82nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 84nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US8614223, 73 | US10858323, Compound 1)
Affinity DataIC50: 94nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50: 105nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US8614223, 73 | US10858323, Compound 1)
Affinity DataIC50: 128nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 3(Human)
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US8614223, 73 | US10858323, Compound 1)
Affinity DataIC50: 158nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent