Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 9548
TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473792(1-(3-methyl-2,4-dimethoxyphenyl)-3-(2′,4R...)
Affinity DataIC50: 240nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473767(1-(2,4-dihydroxyphenyl)-3-(3',4'-dihydroxyphenyl)-...)
Affinity DataIC50: 500nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473769(1-(2,4-dihydroxyphenyl)-3-(2'-hydroxyphenyl)-1-pro...)
Affinity DataIC50: 700nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473768(1-(2,4-dihydroxyphenyl)-3-(3',4'-dimethoxyphenyl)-...)
Affinity DataIC50: 850nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473770(1-(2,4-dihydroxyphenyl)-3-(2'-methoxyphenyl)-1-pro...)
Affinity DataIC50: 3.00E+3nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473771(1-(2,4-dihydroxyphenyl)-3-(4'-methoxyphenyl)-1-pro...)
Affinity DataIC50: 6.00E+3nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473772(1-(2,4,6-trihydroxyphenyl)-3-(4'-aminophenyl)-1-pr...)
Affinity DataIC50: 8.00E+3nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473773(1-(2,4-dihydroxyphenyl)-3-phenyl-1-propanol | US10...)
Affinity DataIC50: 8.00E+3nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473774(1-(2,4-dihydroxyphenyl)-3-(3'-methoxy-4'-hydroxyph...)
Affinity DataIC50: 8.50E+3nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473775(1-(2-hydroxy-4-methoxyphenyl)-3-(3',4',5'-trimetho...)
Affinity DataIC50: 1.10E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
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TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473791(1-(2-methoxy-4-hydroxyphenyl)-3-(2′-hydroxy-...)
Affinity DataIC50: 2.40E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473776(1-(2-hydroxy-4-methoxyphenyl)-3-(2',4'-dimethoxyph...)
Affinity DataIC50: 2.50E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 2.90E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473777(l-(2-hydroxy-5-methoxyphenyl)-3-(3',4'-dimethoxyph...)
Affinity DataIC50: 3.00E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473779(1-(2-hydroxy-4-methoxyphenyl)-3-(2',3',4',5'-tetra...)
Affinity DataIC50: 7.20E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473778(1-(2,4-dihydroxyphenyl)-2-(4'-methoxyphenyl)-1-eth...)
Affinity DataIC50: 7.70E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473780(3-(5'-chloro-1'-methyl-1'-hydro-imidazol-2'-yl)-1-...)
Affinity DataIC50: 2.25E+5nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473781(1-(4-hydroxyphenyl)-3-(4'-hydroxyphenyl)-1-propano...)
Affinity DataIC50: 3.05E+5nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473782(1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3'-methoxy-4'...)
Affinity DataIC50: 3.75E+5nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473783(1-(2,4-dihydroxyphenyl)-2-(3',4'-dimethoxyphenyl)-...)
Affinity DataIC50: 4.31E+5nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 7.00E+5nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473785(1-(2-hydroxy-5-methoxyphenyl)-3-(2',4'-dimethoxyph...)
Affinity DataIC50: 1.00E+6nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473786(1-(2,4-dihydroxyphenyl)-2-(2',4'-dichlorophenyl)-1...)
Affinity DataIC50: 1.00E+6nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473787(1-(2,4,6-trihydroxyphenyl)-3-(3''-hydroxy-4''-meth...)
Affinity DataIC50: 1.20E+6nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473788(1,3-bis(2,4-dimethoxyphenyl)-propan-1,3-diol | US1...)
Affinity DataIC50: 1.20E+6nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473787(1-(2,4,6-trihydroxyphenyl)-3-(3''-hydroxy-4''-meth...)
Affinity DataIC50: 1.20E+6nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent

TargetPolyphenol oxidase 1(White button mushroom)
Unigen

US Patent
LigandPNGBDBM473790(1-(2,4,6-trimethoxyphenyl)-3-(3',4'-dimethoxypheny...)
Affinity DataIC50: 1.50E+6nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2021
Entry Details
Go to US Patent