Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 9410
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464391(US10792283, Compound 1)
Affinity DataIC50: 0.0430nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464392(US10792283, Compound 2)
Affinity DataIC50: 0.0860nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464397(US10792283, Compound 5)
Affinity DataIC50: 0.140nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464395(US10792283, Compound 3)
Affinity DataIC50: 0.240nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464396(US10792283, Compound 4)
Affinity DataIC50: 0.270nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464400(US10792283, Compound 8)
Affinity DataIC50: 0.970nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hangzhou Zhengxiang Pharmaceuticals

US Patent
LigandPNGBDBM464399(US10792283, Compound 7)
Affinity DataIC50: 2.10nMAssay Description:Enzymatic activity of the class I PI3K isoforms in the presence of the compounds of Table 1 above was measured using a time-resolved fluorescence res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent