Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 9355
TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459214(2-[1-[2-[[(3aR,6aS)-5-methylsulfonyl-1,2,3,3a,4,5,...)
Affinity DataIC50: 0.470nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459211(2-[1-[2-[[(3aR,6aS)-5-cyclopropyl-5-hydroxy-2,3,3a...)
Affinity DataIC50: 0.670nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459201(2-[1-[2-(2-methoxyphenyl)-2-[(2-methylsulfonyl-3,3...)
Affinity DataIC50: 0.810nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459208(2-[1-[2-[[(3aR,6aS)-5-ethyl-5-hydroxy-2,3,3a,4,6,6...)
Affinity DataIC50: 0.880nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459206(2-[1-[2-[[(3aR,6aS)-5-hydroxy-5-(trifluoromethyl)-...)
Affinity DataIC50: 0.890nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459200(2-[1-[2-[[(3aS,6aR)-5-hydroxy-1,2,3,3a,4,5,6,6a-oc...)
Affinity DataIC50: 0.930nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459211(2-[1-[2-[[(3aR,6aS)-5-cyclopropyl-5-hydroxy-2,3,3a...)
Affinity DataIC50: 1.13nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459215(2-[1-[2-[[(1S,3S,5R)-6,8-dioxabicyclo[3.2.1]oct-3-...)
Affinity DataIC50: 1.21nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459203(2-[1-[2-[[(3aR,6aS)-5-hydroxy-5-methyl-2,3,3a,4,6,...)
Affinity DataIC50: 1.43nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459209(2-[1-[2-[[(3aR,6aS)-5,5-difluoro-2,3,3a,4,6,6a-hex...)
Affinity DataIC50: 1.43nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459212(2-[1-[2-[[(3aR,6aS)-5-cyano-5-hydroxy-2,3,3a,4,6,6...)
Affinity DataIC50: 1.43nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459210(2-[1-[2-[[(2S,3aS,6aR)-4,5-dihydroxy-1,2,3,3a,4,5,...)
Affinity DataIC50: 1.55nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459213(2-[1-[2-[[(3aS,6aR)-5-(cyanomethyl)-5-hydroxy-2,3,...)
Affinity DataIC50: 1.56nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
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TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459204(2-[1-[2-[(5-cyano-1,2,3,3a,4,5,6,6a-octahydropenta...)
Affinity DataIC50: 1.64nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459202(2-[1-[2-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenteno[c...)
Affinity DataIC50: 1.76nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459201(2-[1-[2-(2-methoxyphenyl)-2-[(2-methylsulfonyl-3,3...)
Affinity DataIC50: 1.76nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459214(2-[1-[2-[[(3aR,6aS)-5-methylsulfonyl-1,2,3,3a,4,5,...)
Affinity DataIC50: 2.19nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459205(2-[1-[2-[[(3aR,6aS)-5-fluoro-1,2,3,3a,4,5,6,6a-oct...)
Affinity DataIC50: 2.24nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459215(2-[1-[2-[[(1S,3S,5R)-6,8-dioxabicyclo[3.2.1]oct-3-...)
Affinity DataIC50: 2.74nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459209(2-[1-[2-[[(3aR,6aS)-5,5-difluoro-2,3,3a,4,6,6a-hex...)
Affinity DataIC50: 4.07nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459202(2-[1-[2-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenteno[c...)
Affinity DataIC50: 4.24nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459213(2-[1-[2-[[(3aS,6aR)-5-(cyanomethyl)-5-hydroxy-2,3,...)
Affinity DataIC50: 4.80nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459212(2-[1-[2-[[(3aR,6aS)-5-cyano-5-hydroxy-2,3,3a,4,6,6...)
Affinity DataIC50: 5.40nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459208(2-[1-[2-[[(3aR,6aS)-5-ethyl-5-hydroxy-2,3,3a,4,6,6...)
Affinity DataIC50: 5.45nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459204(2-[1-[2-[(5-cyano-1,2,3,3a,4,5,6,6a-octahydropenta...)
Affinity DataIC50: 6.53nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM459210(2-[1-[2-[[(2S,3aS,6aR)-4,5-dihydroxy-1,2,3,3a,4,5,...)
Affinity DataIC50: 8.44nMAssay Description: a. 4.5 μL/well of ACC1/ACC2 working solution (2.22 nM) was added to a 384-well reaction plate (PerkinElmer, 6007290). b. The compound (10 mM) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2021
Entry Details
Go to US Patent