Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 9319
TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458086(US10752604, Example 13)
Affinity DataIC50: 1.20nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458080(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 1.30nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458096(US10752604, Example 62)
Affinity DataIC50: 1.46nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458092(US10752604, Example 53)
Affinity DataIC50: 1.83nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458095(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 2.04nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458090(US10752604, Example 42)
Affinity DataIC50: 2.73nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458083(US10752604, Example 5)
Affinity DataIC50: 2.80nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458081(US10752604, Example 2)
Affinity DataIC50: 3nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458089(Preparation of (2S,3R,4R,5S,6R)-2-(4-ethyl-7-(4-me...)
Affinity DataIC50: 3.68nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM50386885(CANAGLIFLOZIN HYDRATE | CANAGLIFLOZIN | US10752604...)
Affinity DataIC50: 4.90nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458093(US10752604, Example 57)
Affinity DataIC50: 5.86nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458091(US10752604, Example 52)
Affinity DataIC50: 9.04nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458080(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 9.10nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458094(US10752604, Example 58)
Affinity DataIC50: 12.1nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458087(US10752604, Example 16)
Affinity DataIC50: 14.3nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458086(US10752604, Example 13)
Affinity DataIC50: 15nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458097(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 19.1nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458098(US10752604, Example 65)
Affinity DataIC50: 38nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458083(US10752604, Example 5)
Affinity DataIC50: 40nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458089(Preparation of (2S,3R,4R,5S,6R)-2-(4-ethyl-7-(4-me...)
Affinity DataIC50: 41.8nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458090(US10752604, Example 42)
Affinity DataIC50: 60.5nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458081(US10752604, Example 2)
Affinity DataIC50: 76nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458096(US10752604, Example 62)
Affinity DataIC50: 92.7nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458092(US10752604, Example 53)
Affinity DataIC50: 94.7nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458082(US10752604, Example 3)
Affinity DataIC50: 142nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458084(US10752604, Example 6)
Affinity DataIC50: 190nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458095(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 199nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458091(US10752604, Example 52)
Affinity DataIC50: 236nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458094(US10752604, Example 58)
Affinity DataIC50: 289nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458088(US10752604, Example 34)
Affinity DataIC50: 295nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458085(US10752604, Example 7)
Affinity DataIC50: 296nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458093(US10752604, Example 57)
Affinity DataIC50: 373nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458097(Preparation of (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-...)
Affinity DataIC50: 518nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM50386885(CANAGLIFLOZIN HYDRATE | CANAGLIFLOZIN | US10752604...)
Affinity DataIC50: 550nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Je Ii Pharmaceutical

US Patent
LigandPNGBDBM458098(US10752604, Example 65)
Affinity DataIC50: 1.61E+3nMAssay Description:To analyze a sodium-dependent glucose transport, cells for expressing hSGLT1 and hSGLT2 were seeded at 1×105 cells per well into a 96-well culture pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
Go to US Patent