Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 9285
TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455397(US10730882, Example 31 | (R)-3-Phenyl-3-[6-(1H-)
Affinity DataIC50: 10nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455385(US10730882, Example 19 | [(R)-1-(3,4-Difluoro-)
Affinity DataIC50: 10nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455365(US10730882, Example 1 | ((R)-1-Phenyl-ethyl)-[6-(1...)
Affinity DataIC50: 13nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455394(US10730882, Example 28 | [(R)-1-(2-Fluoro-phenyl)-)
Affinity DataIC50: 15nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455375(US10730882, Example 10 | (3-Fluorobenzyl)-[6-(1H-)
Affinity DataIC50: 18nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455400(US10730882, Example 35 | 2-{(R)-1-[6-(1H-)
Affinity DataIC50: 20nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455367(US10730882, Example 3 | ((R)-1-(3-Fluoro-phenyl)-)
Affinity DataIC50: 21nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455368(US10730882, Example 4 | ((R)-1-(4-Fluoro-phenyl)-)
Affinity DataIC50: 22nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
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Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455396(US10730882, Example 30 | N-(3-{(R)-1-[6-(1H-)
Affinity DataIC50: 23nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455369(US10730882, Example 5 | ((S)-2-Hydroxy-1-phenyl-)
Affinity DataIC50: 24nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455384(US10730882, Example 18 | Benzyl-(S)-1-morpholin-)
Affinity DataIC50: 25nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455398(US10730882, Example 33 | [(R)-1-(2,6-Difluoro-)
Affinity DataIC50: 28nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455366(US10730882, Example 2 | ((R)-1-(3-Chloro-phenyl)-)
Affinity DataIC50: 30nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455372(US10730882, Example 7 | Benzyl-[6-(1H-)
Affinity DataIC50: 33nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455393(US10730882, Example 27 | [(R)-1-(3-Methoxy-)
Affinity DataIC50: 41nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455378(US10730882, Example 13 | ((R)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 43nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455391(US10730882, Example 25 | (3,4-Difluoro-benzyl)-[6-)
Affinity DataIC50: 49nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455374(US10730882, Example 9 | (4-Fluorobenzyl)-[6-(1H-)
Affinity DataIC50: 55nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455379(US10730882, Example 14 | ((R)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 57nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455392(US10730882, Example 26 | N-(3-{[6-(1H-)
Affinity DataIC50: 67nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455387(US10730882, Example 21 | Benzyl-[6-(1H-)
Affinity DataIC50: 71nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455380(US10730882, Example 15 | ((R)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 97nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455382(US10730882, Example 16 | N-Benzyl-N',N'-dimethyl-)
Affinity DataIC50: 106nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455373(US10730882, Example 8 | ((R)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 108nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455383(US10730882, Example 17 | Benzyl-(R)-1-morpholin-)
Affinity DataIC50: 110nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455389(US10730882, Example 23 | (3-Methoxy-benzyl)-[6-)
Affinity DataIC50: 118nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455388(US10730882, Example 22 | [6-(3-Methyl-1H-)
Affinity DataIC50: 131nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455376(US10730882, Example 11 | (3-Chlorobenzyl)-[6-(1H-)
Affinity DataIC50: 145nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455370(US10730882, Example 6 | (4-Fluorobenzyl)-[6-(1H-)
Affinity DataIC50: 147nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455386(US10730882, Example 20 | ((R)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 167nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455390(US10730882, Example 24 | (2-Fluoro-benzyl)-[6-(1H-)
Affinity DataIC50: 204nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455399(US10730882, Example 34 | 4-[2-((R)-1-Phenyl-)
Affinity DataIC50: 346nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455395(US10730882, Example 29 | ((S)-1-Phenyl-ethyl)-[6-)
Affinity DataIC50: 3.00E+3nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetRibosomal protein S6 kinase beta-1(Human)
Sentinel Oncology

US Patent
LigandPNGBDBM455377(US10730882, Example 12 | ((R)-1-Phenyl-ethyl)-[7-)
Affinity DataIC50: 3.00E+3nMAssay Description:In a final reaction volume of 25 μL, p70S6K (h) (5-10 mU) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM KKRNRTLTV, 10 mM Mg aceta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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