Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 9275
TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM454531(US10730860, TABLE 1.1)
Affinity DataKd:  483nMAssay Description:ITC was performed using a ITC200 microcalorimeter from GE (Northampton, Mass.). All experiments were carried out at 25° C. while stirring at 1000 rpm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
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TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 850nMAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM454531(US10730860, TABLE 1.1)
Affinity DataIC50: 1.98E+3nMAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2021
Entry Details
Go to US Patent