Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 9253
LigandPNGBDBM453207(1-(5-fluoro-2-methoxy-4-(4,4,4-trifluoro-3,3- dime...)
Affinity DataIC50: 1.20nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453206(1-(4-((4,4-difluorocyclohexyl)ethynyl)-5-fluoro-2-...)
Affinity DataIC50: 3.30nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM217959(US9212182, 643 | US10729684, Example 10)
Affinity DataIC50: 4.53nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
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LigandPNGBDBM453211(1-(5-fluoro-2-methoxy-4-(((1R,2S)-2- (trifluoromet...)
Affinity DataIC50: 5.5nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453210(1-(5-fluoro-2-methoxy-4-(((1R,2S)-2- (trifluoromet...)
Affinity DataIC50: 6.80nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453209(1-(5-fluoro-2-methoxy-4-(((1R,2S)-2-(trifluorometh...)
Affinity DataIC50: 7nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453208(1-(4-(cyclopentylethynyl)-2-methoxyphenyl)-N-3- is...)
Affinity DataIC50: 7.5nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453214(1-(5-chloro-4-(cyclopentylethynyl)-2- methoxypheny...)
Affinity DataIC50: 7.80nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453212(1-(5-fluoro-2-methoxy-4-(((1R,2R)-2- (trifluoromet...)
Affinity DataIC50: 8nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM217977(US9212182, 645 | US10729684, Example 9)
Affinity DataIC50: 8.95nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453215(1-(4-(((1R)-3,3-difluorocyclohexyl)ethynyl)-5-fluo...)
Affinity DataIC50: 9.73nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453213(1-(5-fluoro-2-methoxy-4-((1- (trifluoromethyl)cycl...)
Affinity DataIC50: 10nMAssay Description:HEK 293 Cells stably transfected with either Nav 1.7 or Nav 1.5 were recorded in population patch-clamp mode with the IonWorks Quattro automated elec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM217959(US9212182, 643 | US10729684, Example 10)
Affinity DataIC50: 17.3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453213(1-(5-fluoro-2-methoxy-4-((1- (trifluoromethyl)cycl...)
Affinity DataIC50: 18.6nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
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Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM217977(US9212182, 645 | US10729684, Example 9)
Affinity DataIC50: 19.3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453207(1-(5-fluoro-2-methoxy-4-(4,4,4-trifluoro-3,3- dime...)
Affinity DataIC50: 27.8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453215(1-(4-(((1R)-3,3-difluorocyclohexyl)ethynyl)-5-fluo...)
Affinity DataIC50: 33.8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453206(1-(4-((4,4-difluorocyclohexyl)ethynyl)-5-fluoro-2-...)
Affinity DataIC50: 44.6nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453208(1-(4-(cyclopentylethynyl)-2-methoxyphenyl)-N-3- is...)
Affinity DataIC50: 49.7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453209(1-(5-fluoro-2-methoxy-4-(((1R,2S)-2-(trifluorometh...)
Affinity DataIC50: 57.8nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453212(1-(5-fluoro-2-methoxy-4-(((1R,2R)-2- (trifluoromet...)
Affinity DataIC50: 62nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453214(1-(5-chloro-4-(cyclopentylethynyl)-2- methoxypheny...)
Affinity DataIC50: 66.7nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453211(1-(5-fluoro-2-methoxy-4-(((1R,2S)-2- (trifluoromet...)
Affinity DataIC50: 139nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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LigandPNGBDBM453210(1-(5-fluoro-2-methoxy-4-(((1R,2S)-2- (trifluoromet...)
Affinity DataIC50: 210nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
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