Compile Data Set for Download or QSAR
Report error Found 98 Enz. Inhib. hit(s) with all data for entry = 9194
TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448395(US10695334, Example 23 | 7-[(2-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448404(US10695334, Example 71 | 1-{[6-(3-Cyano-3-methylpy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448402(US10695334, Example 54 | 1-[(6-{2-Azaspiro[3.31]he...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448401(US10695334, Example 52 | N-[(6R)-3-Methyl-2H,4H,5H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448421(US10695334, Example 48 | 1-[(6-{3-Azabicyclo[4.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448400(US10695334, Example 47 | N-[(6R)-3-Methyl-2H,4H,5H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448399(US10695334, Example 46 | 1-({6-[3-(Difluoromethyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448420(US10695334, Example 45 | 1-[(6-{5-Azaspiro[2.4]hep...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448398(US10695334, Example 37 | 1-{[6-(3,3-Difluoropyrrol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448397(US10695334, Example 36 | 1-[(6-{6-Azaspiro[3.4]oct...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448396(US10695334, Example 35 | 1{[6-(3,3-Dimethylpyrroli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448419(US10695334, Example 33 | 7-[(2-{5-Azaspiro[2.3]hex...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448418(US10695334, Example 25 | 1-[(2-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448405(US10695334, Example 77 | 1-{[6-(3-Fluoro-3-methyla...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448394(US10695334, Example 22 | 1-[(6-{5-Azaspiro[2.3]hex...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448393(US10695334, Example 21 | 7-[(2-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448392(US10695334, Example 20 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448391(US10695334, Example 19 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448390(US10695334, Example 18 | 1-[(6-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448388(US10695334, Example 17 | 7-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448387(US10695334, Example 16 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448386(US10695334, Example 15 | 1-[(6-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448385(US10695334, Example 14 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448384(US10695334, Example 13 | 7-[(6-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448383(US10695334, Example 12 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448407(US10695334, Example 96 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448432(US10695334, Example 109 | 5-[(6-{3-Azabicyclo[3.1....)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448417(US10695334, Example 108 | 1-[(6-{3-Azabicyclo[3.1....)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448416(US10695334, Example 105 | 1-[(6-{3-Azabicyclo[3.1....)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448415(US10695334, Example 104 | 1-[(6-{5-Azaspiro[2.3]he...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448414(US10695334, Example 103 | 1-[(6-{3-Azabicyclo[3.1....)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448413(US10695334, Example 102 | 1-[(6-{3-Azabicyclo[3.1....)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448412(US10695334, Example 101 | 1-({4-Methyl-2-[(1R,5S,6...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448411(US10695334, Example 100 | N-[(6R)-3-Methyl-2H,4H,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448410(US10695334, Example 99 | 1-({6-[(1R,5S,6S)-6-(Hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448409(US10695334, Example 98 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448408(US10695334, Example 97 | 1-[(6-(3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448382(US10695334, Example 11 | 1-[(6-{5-azaspiro[2.3]hex...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448431(US10695334, Example 94 | 1-({6-[(1R,5S,6R)-6-(hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448430(US10695334, Example 93 | 1-[(2-{5-Azaspiro[2.3]hex...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448429(US10695334, Example 92 | 1-[(2-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448428(US10695334, Example 90 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448427(US10695334, Example 89 | 1-[(6-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448426(US10695334, Example 88 | 1-[(6-{5-Azaspiro[2.3]hex...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448406(US10695334, Example 87 | 1-[(2-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448425(US10695334, Example 86 | 1-[(6-{3-Azabicyclo[3.1.0...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448424(US10695334, Example 84 | 1-[(2-{6,6-Difluoro-3-aza...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448423(US10695334, Example 82 | N-[(6R)-3-Methyl-2H,4H,5H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448422(US10695334, Example 79 | N-[(6R)-3-Methyl-2H,4H,5H...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetThymidine kinase, cytosolic(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM448381(US10695334, Example 9 | 2-[(6-{3-Azabicyclo[3.1.0]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Prior to the assay, human TK1 (R&D Systems) was activated by incubation with human trypsin (Calbiochem) in a 1:10,000 ratio for 15 min at 37° C. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

Displayed 1 to 50 (of 98 total ) | Next | Last >>
Jump to: