Compile Data Set for Download or QSAR
Report error Found 96 Enz. Inhib. hit(s) with all data for entry = 9151
TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116254(US8637508, 31 | US10035794, Example 31 | US1068328...)
Affinity DataIC50: 1nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116236(US8637508, 11 | US10035794, Example 11 | US1068328...)
Affinity DataIC50: 4nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM445520(US10683287, Example 46)
Affinity DataIC50: 5nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116245(US8637508, 22 | US10035794, Example 22 | US1068328...)
Affinity DataIC50: 5nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116233(US8637508, 8 | US10035794, Example 8 | US10683287,...)
Affinity DataIC50: 5nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116247(US8637508, 24 | US10035794, Example 24 | US1068328...)
Affinity DataIC50: 6nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116255(US8637508, 32 | US10035794, Example 32 | US1068328...)
Affinity DataIC50: 7nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116254(US8637508, 31 | US10035794, Example 31 | US1068328...)
Affinity DataIC50: 7nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 7nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM445495(US10683287, Example 21)
Affinity DataIC50: 8nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116247(US8637508, 24 | US10035794, Example 24 | US1068328...)
Affinity DataIC50: 10nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM445520(US10683287, Example 46)
Affinity DataIC50: 10nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116244(US8637508, 20 | US10035794, Example 20 | US1068328...)
Affinity DataIC50: 10nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116250(US8637508, 27 | US10035794, Example 27 | US1068328...)
Affinity DataIC50: 11nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116236(US8637508, 11 | US10035794, Example 11 | US1068328...)
Affinity DataIC50: 12nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116250(US8637508, 27 | US10035794, Example 27 | US1068328...)
Affinity DataIC50: 12nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116245(US8637508, 22 | US10035794, Example 22 | US1068328...)
Affinity DataIC50: 13nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116248(US8637508, 25 | US10035794, Example 25 | US1068328...)
Affinity DataIC50: 15nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116233(US8637508, 8 | US10035794, Example 8 | US10683287,...)
Affinity DataIC50: 20nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116252(US8637508, 29 | US10035794, Example 29 | US1068328...)
Affinity DataIC50: 24nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM445503(US10683287, Example 29)
Affinity DataIC50: 24nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116252(US8637508, 29 | US10035794, Example 29 | US1068328...)
Affinity DataIC50: 25nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM445503(US10683287, Example 29)
Affinity DataIC50: 26nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116257(US8637508, 34 | US10035794, Example 34 | US1068328...)
Affinity DataIC50: 30nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM445495(US10683287, Example 21)
Affinity DataIC50: 31nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116261(US8637508, 38 | US10035794, Example 38 | US1068328...)
Affinity DataIC50: 33nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116235(US8637508, 10 | US10035794, Example 10 | US1068328...)
Affinity DataIC50: 39nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116267(US8637508, 44 | US10035794, Example 44 | US1068328...)
Affinity DataIC50: 40nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116244(US8637508, 20 | US10035794, Example 20 | US1068328...)
Affinity DataIC50: 41nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116263(US8637508, 40 | US10035794, Example 40 | US1068328...)
Affinity DataIC50: 42nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116243(US8637508, 19 | US10035794, Example 19 | US1068328...)
Affinity DataIC50: 43nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116255(US8637508, 32 | US10035794, Example 32 | US1068328...)
Affinity DataIC50: 45nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116240(US8637508, 16 | US10035794, Example 16 | US1068328...)
Affinity DataIC50: 55nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116243(US8637508, 19 | US10035794, Example 19 | US1068328...)
Affinity DataIC50: 82nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116240(US8637508, 16 | US10035794, Example 16 | US1068328...)
Affinity DataIC50: 82nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116248(US8637508, 25 | US10035794, Example 25 | US1068328...)
Affinity DataIC50: 93nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116235(US8637508, 10 | US10035794, Example 10 | US1068328...)
Affinity DataIC50: 100nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116247(US8637508, 24 | US10035794, Example 24 | US1068328...)
Affinity DataIC50: 120nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116242(US8637508, 18 | US10683287, Example 18)
Affinity DataIC50: 130nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116264(US8637508, 41 | US10035794, Example 41 | US1068328...)
Affinity DataIC50: 130nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116242(US8637508, 18 | US10683287, Example 18)
Affinity DataIC50: 140nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116247(US8637508, 24 | US10035794, Example 24 | US1068328...)
Affinity DataIC50: 150nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116261(US8637508, 38 | US10035794, Example 38 | US1068328...)
Affinity DataIC50: 160nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116263(US8637508, 40 | US10035794, Example 40 | US1068328...)
Affinity DataIC50: 170nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116267(US8637508, 44 | US10035794, Example 44 | US1068328...)
Affinity DataIC50: 180nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116265(US8637508, 42 | US10035794, Example 42 | US1068328...)
Affinity DataIC50: 200nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM116264(US8637508, 41 | US10035794, Example 41 | US1068328...)
Affinity DataIC50: 230nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM445480(US10683287, Example 6)
Affinity DataIC50: 240nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 2(Human)
Novartis

US Patent
LigandPNGBDBM116227(US8637508, 1 | US10035794, Example 1 | US10683287,...)
Affinity DataIC50: 260nMAssay Description:Recombinant BACE-2 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM445479(US10683287, Example 5)
Affinity DataIC50: 270nMAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
Go to US Patent

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