Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 9232
TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180306(8-(6-bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-iso...)
Affinity DataEC50:  38.8nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180308(2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-9-...)
Affinity DataEC50:  22.3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataEC50:  10nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180301(2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-9-...)
Affinity DataEC50:  50.4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180305(2-fluoro-8-(6-chloro-benzo[1,3]dioxol-5-ylmethyl)-...)
Affinity DataEC50:  77.2nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180310(2-fluoro-8-(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-9...)
Affinity DataEC50:  56.5nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180303(2-fluoro-8-(2-iodo-4,5-dimethoxy-benzyl)-9-(pent-4...)
Affinity DataEC50: >1.50E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM450875(US10676476, Example 4)
Affinity DataEC50:  1.54E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180304(2-fluoro-8-(2-bromo-4,5-dimethoxy-benzyl)-9-(pent-...)
Affinity DataEC50: >1.50E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165313(8-(2,4-Dichloro-5-methoxy-phenylsulfanyl)-9-(2-iso...)
Affinity DataEC50:  5.00E+3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180309(2-fluoro-8-(2-chloro-4,5-dimethoxy-benzyl)-9-(pent...)
Affinity DataEC50:  4.60E+3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165315(9-Pent-4-ynyl-8-(2,4,5-trichloro-phenylsulfanyl)-9...)
Affinity DataEC50:  8.50E+3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165281(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-flu...)
Affinity DataEC50:  120nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165272(8-(6-bromobenzo[d][1,3]dioxol-5-ylthio)-9-(pent-4-...)
Affinity DataEC50:  50.8nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-alpha(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165272(8-(6-bromobenzo[d][1,3]dioxol-5-ylthio)-9-(pent-4-...)
Affinity DataEC50:  30nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180301(2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-9-...)
Affinity DataIC50: 80nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180308(2-fluoro-8-(6-iodo-benzo[1,3]dioxol-5-ylmethyl)-9-...)
Affinity DataIC50: 90nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180302(8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPRO...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180306(8-(6-bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-iso...)
Affinity DataIC50: 205nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180310(2-fluoro-8-(6-bromo-benzo[1,3]dioxol-5-ylmethyl)-9...)
Affinity DataIC50: 210nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165272(8-(6-bromobenzo[d][1,3]dioxol-5-ylthio)-9-(pent-4-...)
Affinity DataIC50: 300nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180305(2-fluoro-8-(6-chloro-benzo[1,3]dioxol-5-ylmethyl)-...)
Affinity DataIC50: 300nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165272(8-(6-bromobenzo[d][1,3]dioxol-5-ylthio)-9-(pent-4-...)
Affinity DataIC50: 365nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165281(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-flu...)
Affinity DataIC50: 1.30E+3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180309(2-fluoro-8-(2-chloro-4,5-dimethoxy-benzyl)-9-(pent...)
Affinity DataIC50: 3.00E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM450875(US10676476, Example 4)
Affinity DataIC50: 4.78E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180303(2-fluoro-8-(2-iodo-4,5-dimethoxy-benzyl)-9-(pent-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50180304(2-fluoro-8-(2-bromo-4,5-dimethoxy-benzyl)-9-(pent-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165315(9-Pent-4-ynyl-8-(2,4,5-trichloro-phenylsulfanyl)-9...)
Affinity DataIC50: 5.80E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sloan-Kettering Institute For Cancer Research

US Patent
LigandPNGBDBM50165313(8-(2,4-Dichloro-5-methoxy-phenylsulfanyl)-9-(2-iso...)
Affinity DataIC50: 5.83E+4nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent