Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 9025
TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435739(US10611751, Example 1 | 2-(2,6-dichlorophenyl)-1-(...)
Affinity DataEC50:  16.4nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435762(US10611751, Example 2 | 2-(2,6-dichlorophenyl)-1- ...)
Affinity DataEC50:  172nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435774(US10611751, Example 3 | 1-((1S,3R)-5-(1-cyclopropy...)
Affinity DataEC50:  287nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435778(US10611751, Example 4 | 2-(2,6-dichlorophenyl)-1- ...)
Affinity DataEC50:  28.5nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435791(US10611751, Example 5 | 1-((1S,3R)-5-(1-(2-(l1- ox...)
Affinity DataEC50:  18.3nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435884(US10611751, Example 6 | 2-(2-chloro-6-fluorophenyl...)
Affinity DataEC50:  42.2nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435897(US10611751, Example 7 | 2-(2-chlorophenyl)-1-((1S,...)
Affinity DataEC50:  81.2nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435904(US10611751, Example 8 | 2-(2,6-dichlorophenyl)-1-(...)
Affinity DataEC50:  13.4nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435952(US10611751, Example 9 | 2-(2-chloro-6-fluorophenyl...)
Affinity DataEC50:  28nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM435987(US10611751, Example 10 | 2-(2,6-difluorophenyl)-1-...)
Affinity DataEC50:  127nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM436043(US10611751, Example 11 | 2-(2-chloro-5-fluoropheny...)
Affinity DataEC50:  112nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM436044(US10611751, Example 12 | 2-(2-chloro-4-fluoropheny...)
Affinity DataEC50:  540nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM436045(US10611751, Example 13 | 2-(2-fluorophenyl)-1-((1S...)
Affinity DataEC50:  484nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM436046(US10611751, Example 14 | 2-(2,3-difluorophenyl)-1-...)
Affinity DataEC50:  677nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
Entry Details
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TargetD(1A) dopamine receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM436047(US10611751, Example 15 | 2-(2,5-difluorophenyl)-1-...)
Affinity DataEC50:  836nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
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