Compile Data Set for Download or QSAR
Report error Found 121 Enz. Inhib. hit(s) with all data for entry = 9036
LigandPNGBDBM300972(5-((6S,8R)-1- fluoro-8- methyl-7- (2,2,2- trifluor...)
Affinity DataIC50: 0.690nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300961(1-(3-Fluoropropyl)-N-(4-((6R,8R)-8-methyl-7-(2,2,2...)
Affinity DataIC50: 0.810nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM436275(US10590130, Example 61 | 2,2-difluoro-3- ((6S,8R)-...)
Affinity DataIC50: 0.880nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300973(2-fluoro-6- ((6S,8R)-1- fluoro-8- methyl-7- (2,2,2...)
Affinity DataIC50: 0.940nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300996(2,2-difluoro-3- ((6S,8R)-1- fluoro-6-(6- fluoro-5-...)
Affinity DataIC50: 1nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300981(6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...)
Affinity DataIC50: 1.20nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300974(6-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-5-...)
Affinity DataIC50: 1.30nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300967(5-Fluoro-6-((6S,8R)-1-fluoro-8-methyl-7-(2,2,2-tri...)
Affinity DataIC50: 1.40nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300969(US10961241, Example 36 | BDBM300970 | US10961241, ...)
Affinity DataIC50: 1.5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300982(N-(4-((6R,8R)- 7-(2,2- difluoroethyl)- 8-methyl- 6...)
Affinity DataIC50: 1.5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300983(N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 8-methyl- 6...)
Affinity DataIC50: 1.5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300963(2-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6...)
Affinity DataIC50: 1.60nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300979(N-(4-((6S,8R)- 7-(2,2- difluoroethyl)- 6,8-dimethy...)
Affinity DataIC50: 1.60nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300964(5-fluoro-N-(1-(3-fluoropropyl)azetidin-3-yl)-6-((6...)
Affinity DataIC50: 1.80nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300969(US10961241, Example 36 | BDBM300970 | US10961241, ...)
Affinity DataIC50: 1.80nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300968(N-(1-(3- fluoropropyl) azetidin-3-yl)- N-methyl-6-...)
Affinity DataIC50: 1.90nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300933(N-(3,5-difluoro-4-((6S,8R)-8-methyl-7-(2,2,2-trifl...)
Affinity DataIC50: 2nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM301005(5-fluoro-N-(1- (3- fluoropropyl) azetidin-3-yl)-6-...)
Affinity DataIC50: 2nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300955(N-(4-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8...)
Affinity DataIC50: 2.10nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300969(US10961241, Example 36 | BDBM300970 | US10961241, ...)
Affinity DataIC50: 2.10nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300992(2,2-difluoro-3- ((6S,8R)-6-(5- ((1-(3- fluoropropy...)
Affinity DataIC50: 2.10nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300929(3-((6S,8R)-6-(2,6-difluoro-4-((1-(3-fluoropropyl)a...)
Affinity DataIC50: 2.20nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300945(N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...)
Affinity DataIC50: 2.40nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300969(US10961241, Example 36 | BDBM300970 | US10961241, ...)
Affinity DataIC50: 2.40nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300975(N-(2-fluoro-4- ((6R,8R)-8- methyl-7- (2,2,2- trifl...)
Affinity DataIC50: 2.40nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300953(N-(4-((6S,8R)-7-(2,2-difluoropropyl)-8-methyl-6,7,...)
Affinity DataIC50: 2.60nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300984(5-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...)
Affinity DataIC50: 2.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300921(6-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-meth...)
Affinity DataIC50: 2.80nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300985(6-((6S,8S)-7- (2,2- difluoroethyl)- 8- (difluorome...)
Affinity DataIC50: 2.80nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM301006((S)-6-(8,8- dimethyl-7- (2,2,2- trifluoroethyl)- 6...)
Affinity DataIC50: 2.90nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM301007((S)-6-(7-(2,2- difluoroethyl)- 8,8-dimethyl- 6,7,8...)
Affinity DataIC50: 3.40nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300945(N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...)
Affinity DataIC50: 3.5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300980(6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...)
Affinity DataIC50: 3.60nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300919(N-(4-((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-8-m...)
Affinity DataIC50: 3.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300976(N-(1-(3- fluoropropyl) azetidin-3-yl)-5- ((6S,8R)-...)
Affinity DataIC50: 3.80nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300959(6-((6S,8R)-7-(2,2-difluoroethyl)-8-methyl-6,7,8,9-...)
Affinity DataIC50: 4.10nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300977(6-((6S,8R)-7- (2,2- difluoroethyl)- 8-methyl- 6,7,...)
Affinity DataIC50: 4.10nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300997(6-((6S,8R)-7- (2-fluoro-2- methylpropyl)- 8-methyl...)
Affinity DataIC50: 4.30nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM436274(US10590130, Example 60 | 2,2-difluoro-3- ((6S,8R)-...)
Affinity DataIC50: 4.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300991(6-((6S,8R)-7- ((1- fluorocyclo- propyl)methyl)-8- ...)
Affinity DataIC50: 5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM301001(US10131663, Example 67 | BDBM301002 | 1-(3- fluoro...)
Affinity DataIC50: 5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300999(US10131663, Example 66 | 6-((6S,8R)-7- (2- fluorop...)
Affinity DataIC50: 5.30nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300956((6S,8R)-7-(2,2-difluoroethyl)-6-(4-((1-(3-fluoropr...)
Affinity DataIC50: 5.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300962(1-(3-fluoropropyl)-N-(3-methoxy-4-((6S,8R)-8-methy...)
Affinity DataIC50: 5.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300987(N-(2-fluoro-4- ((6S,8R)-7-((1- fluorocyclo- propyl...)
Affinity DataIC50: 5.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300998(N-(4-((6S,8R)- 7-(2-fluoro-2- methylpropyl)- 8-met...)
Affinity DataIC50: 6.10nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300999(US10131663, Example 66 | 6-((6S,8R)-7- (2- fluorop...)
Affinity DataIC50: 6.20nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300924(6-((6S,8R)-7-((1-fluorocyclopropyl)methyl)-8-methy...)
Affinity DataIC50: 6.5nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300945(N-(4-((6S,8R)-7-(2-fluoro-3-methoxy-2-methylpropyl...)
Affinity DataIC50: 6.60nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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LigandPNGBDBM300960((6S,8R)-7-(2,2-difluoroethyl)-6-(5-((1-(3-fluoropr...)
Affinity DataIC50: 6.70nMAssay Description:hERG (human ether go go-related gene) potassium channels are essential for normal electrical activity in the heart. Arrhythmia can be induced by a bl...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2020
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