Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 9003
TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285658(US10077273, Compound 4 | US10584132, Compound 4 | ...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285660(US10077273, Compound 1 | US10584132, Compound 1 | ...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285660(US10077273, Compound 1 | US10584132, Compound 1 | ...)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285661(US10077273, Compound 69 | US10584132, Compound 69 ...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285662(US10077273, Compound 70 | US10584132, Compound 70 ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285663(US10077273, Compound 11 | US10584132, Compound 11 ...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285659(US10077273, Compound 68 | US10584132, Compound 68 ...)
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285664(US10077273, Compound 71 | US10584132, Compound 71 ...)
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285666(US10077273, Compound 2 | US10584132, Compound 2 | ...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285665(US10077273, Compound 72 | US10584132, Compound 72 ...)
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285667(US10077273, Compound 73 | US10584132, Compound 73 ...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, cytosolic(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285669(US10077273, Compound 74 | US10584132, Compound 74 ...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent

TargetSerine hydroxymethyltransferase, mitochondrial(Human)
The Trustees of Princeton University

US Patent
LigandPNGBDBM285668(US10077273, Compound 8 | US10584132, Compound 8 | ...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human SHMT by compounds in this disclosure is evaluated, for example, in their racemic forms in an in vitro assay. For example, Compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
Go to US Patent