Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 8996
TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434982(US10584104, Compound of Example 51 | US11149013, C...)
Affinity DataIC50: 81nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434983(US10584104, Compound of Example 52)
Affinity DataIC50: 83nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434973(US10584104, Compound of Example 10)
Affinity DataIC50: 94nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434978(US10584104, Compound of Example 38)
Affinity DataIC50: 107nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434970(US10584104, Compound of Example 2)
Affinity DataIC50: 193nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434969(US10584104, Compound of Example 1)
Affinity DataIC50: 201nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434979(US10584104, Compound of Example 39)
Affinity DataIC50: 381nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434971(US10584104, Compound of Example 5)
Affinity DataIC50: 418nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434972(US10584104, Compound of Example 6)
Affinity DataIC50: 440nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434974(US10584104, Compound of Example 11)
Affinity DataIC50: 484nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434981(US10584104, Compound of Example 49)
Affinity DataIC50: 487nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434980(US10584104, Compound of Example 48)
Affinity DataIC50: 512nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434976(US10584104, Compound of Example 20)
Affinity DataIC50: 886nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434977(US10584104, Compound of Example 25)
Affinity DataIC50: 1.01E+3nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434975(US10584104, Compound of Example 17)
Affinity DataIC50: 1.02E+3nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434968(US10584104, Compound B)
Affinity DataIC50: 1.81E+3nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434966(US10584104, Compound A)
Affinity DataIC50: 2.13E+3nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
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Date in BDB:
11/29/2020
Entry Details
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TargetSolute carrier family 22 member 12(Human)
Tianjin Institute of Pharmaceutical Research

US Patent
LigandPNGBDBM434965(US10584104, Compound lesinurad)
Affinity DataIC50: 7.18E+3nMAssay Description:After trypsin digestion, the expression cells (HEK293) stably expressing URAT1 gene and mock cells were all inoculated into lysine-coated 24-well cul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
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