Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 8963
TargetGlutaminase kidney isoform, mitochondrial(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM332752(US10196382, Example 1 | (2S)-2-[3-(Difluoromethoxy...)
Affinity DataIC50: 24.7nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
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TargetGlutaminase kidney isoform, mitochondrial(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM332757(US10196382, Example 6 | N-[6-[(3R)-3-(Pyridazin-3-...)
Affinity DataIC50: 25.2nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM332754(US10196382, Example 3 | (2S)-2-Methoxy-2-(3-methox...)
Affinity DataIC50: 29.8nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM332756(US10196382, Example 5 | N-[6-[(3R)-3-(Pyridazin-3-...)
Affinity DataIC50: 30.6nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM332755(US10196382, Example 4 | 2-(2-Methoxyphenyl)-N-[6-[...)
Affinity DataIC50: 30.9nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent

TargetGlutaminase kidney isoform, mitochondrial(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM332753(US10196382, Example 2 | (2S)-2-[3-(Trifluoromethox...)
Affinity DataIC50: 95.7nMAssay Description:A Glutamate Oxidase/AmplexRed coupled assay was used to measure the ability of compounds to bind to and inhibit the activity of GLS1 in vitro. 6His t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2020
Entry Details
Go to US Patent