Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 8968
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433315(US10561655, Compound 108 | (S)-3-(1-amino-1,3- dih...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433314(US10561655, Compound 86 | 3-(6-amino-3- azabicyclo...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433317(US10561655, Compound 88 | (S)-3-(4-amino-2-oxa-8- ...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433316(US10561655, Compound 87 | (R)-3-(3-amino-3H- spiro...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433311(US10561655, Compound 82 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433310(US10561655, Compound 109 | 3-((3S,4S)-4-amino-3- m...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433313(US10561655, Compound 13 | 3-(2- aminospiro[bicyclo...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433312(US10561655, Compound 83 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433290(US10561655, Compound 2 | 3-(4-(aminomethyl)-4- met...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433292(US10561655, Compound 52 | 6-amino-2-(3- (aminometh...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433291(US10561655, Compound 35 | 6-(4-(aminomethyl)-4- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433307(US10561655, Compound 81 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433306(US10561655, Compound 80 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433309(US10561655, Compound 107 | 3-((3S,4S)-4-amino-3- m...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433308(US10561655, Compound 84 | 4-((5-(4-(aminomethyl)-4...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433303(US10561655, Compound 74 | 1-(3-aminocyclohexyl)-4-...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433302(US10561655, Compound 73 | (S)-3-(4-amino-2-oxa-8- ...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433305(US10561655, Compound 79 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433304(US10561655, Compound 33 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433298(US10561655, Compound 28 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433297(US10561655, Compound 32 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433301(US10561655, Compound 14 | 3-((3S,4S)-4-amino-3- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433300(US10561655, Compound 30 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433294(US10561655, Compound 77 | 6-((2-amino-3- chloropyr...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433293(US10561655, Compound 34 | 6-(4-(aminomethyl)-4- me...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433296(US10561655, Compound 29 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Synblia Therapeutics

US Patent
LigandPNGBDBM433295(US10561655, Compound 31 | N-(3-((5-(4- (aminomethy...)
Affinity DataIC50: 50nMAssay Description:IC50 values were determined at room temperature in 384-well black polystyrene plate, using a final reaction volume of 15 μl and the following as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent