Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 8910
TargetBeta-lactamase(Escherichia coli)
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50: 8nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
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TargetBeta-lactamase TEM(Escherichia coli)
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50: 52nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella oxytoca)
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50: 91nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetBeta-lactamase(Escherichia coli)
Fedora Pharmaceuticals

US Patent
LigandPNGBDBM428643(US10544146, Ex. 40)
Affinity DataIC50: 327nMAssay Description:he inhibitory activities of present compounds against various enzymes were measured by spectrophotometric assay using 490 nM and using nitrocefin as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent