Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 8894
TargetThyroid hormone receptor alpha(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  1.01nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
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TargetThyroid hormone receptor beta(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataEC50:  1.49nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
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TargetThyroid hormone receptor alpha(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataEC50:  74.7nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
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PDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM50115668([4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phe...)
Affinity DataEC50:  2.82nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
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PDB3D3D Structure (crystal)
TargetThyroid hormone receptor alpha(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM426634(US10544075, Compound JD-20)
Affinity DataEC50:  7.96nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetThyroid hormone receptor beta(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM426634(US10544075, Compound JD-20)
Affinity DataEC50:  0.880nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetThyroid hormone receptor alpha(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM426635(US10544075, Compound JD-21)
Affinity DataEC50:  7.82nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetThyroid hormone receptor beta(Human)
Oregon Health & Science University

US Patent
LigandPNGBDBM426635(US10544075, Compound JD-21)
Affinity DataEC50:  1.24nMAssay Description:Human epithelial kidney cells (HEK 293) were grown to 80% confluency in Dubelcco's modified Eagles 4.5 g/L glucose medium (high glucose DMEM) con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent