Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 8880
LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 36nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM426311(US10513524, Compound (P1))
Affinity DataIC50: 42nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 49nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataIC50: 70nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
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PDB3D3D Structure (crystal)
LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 1.01E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataIC50: 2.50E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 3.00E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 5.28E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
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LigandPNGBDBM426311(US10513524, Compound (P1))
Affinity DataIC50: 4.51E+4nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent