Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 8817
LigandPNGBDBM420317(5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-...)
Affinity DataIC50: 13nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM420310(2-Methyl-3-[(1-methylethyl)amino]-N-[(6-methyl-2-o...)
Affinity DataIC50: 40nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM420312(5-Bromo-2-methyl-3-[(1-methylethyl)amino]-N-{[6-me...)
Affinity DataIC50: 50nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM420316(2,5-Dichloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-...)
Affinity DataIC50: 250nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM420317(5-Bromo-3-(sec-butoxy)-N-((4,6-dimethyl-2-oxo-1,2-...)
Affinity DataIC50: 316nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM420308(5-Bromo-2-methyl-3-[(1-methylethyl)amino]-N-[(6-me...)
Affinity DataIC50: 501nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM420319(5 Chloro-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyri...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
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Date in BDB:
9/25/2020
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LigandPNGBDBM50193711(CHEMBL3955846 | US10478426, Example 36)
Affinity DataIC50: 2.50E+3nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2020
Entry Details
Go to US Patent