Compile Data Set for Download or QSAR
Report error Found 346 Enz. Inhib. hit(s) with all data for entry = 8789
TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419721(US10464919, Example 59)
Affinity DataIC50: 0.920nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419799(US10464919, Example 137)
Affinity DataIC50: 0.950nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419844(US10464919, Example 182)
Affinity DataIC50: 1.26nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419794(US10464919, Example 132)
Affinity DataIC50: 1.31nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419731(US10464919, Example 69)
Affinity DataIC50: 1.32nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419721(US10464919, Example 59)
Affinity DataIC50: 1.37nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419781(US10464919, Example 119)
Affinity DataIC50: 1.38nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419751(US10464919, Example 89)
Affinity DataIC50: 1.48nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419791(US10464919, Example 129)
Affinity DataIC50: 1.65nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419758(US10464919, Example 96)
Affinity DataIC50: 1.75nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419797(US10464919, Example 135)
Affinity DataIC50: 1.75nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419740(US10464919, Example 78)
Affinity DataIC50: 1.87nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419721(US10464919, Example 59)
Affinity DataIC50: 1.95nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419832(US10464919, Example 170)
Affinity DataIC50: 1.96nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419755(US10464919, Example 93)
Affinity DataIC50: 1.97nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419761(US10464919, Example 99)
Affinity DataIC50: 1.99nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419765(US10464919, Example 103)
Affinity DataIC50: 2.10nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419842(US10464919, Example 180)
Affinity DataIC50: 2.12nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419751(US10464919, Example 89)
Affinity DataIC50: 2.35nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419784(US10464919, Example 122)
Affinity DataIC50: 2.37nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419785(US10464919, Example 123)
Affinity DataIC50: 2.38nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419804(US10464919, Example 142)
Affinity DataIC50: 2.45nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419812(US10464919, Example 150)
Affinity DataIC50: 2.49nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419803(US10464919, Example 141)
Affinity DataIC50: 2.62nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419796(US10464919, Example 134)
Affinity DataIC50: 2.70nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419794(US10464919, Example 132)
Affinity DataIC50: 2.77nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419793(US10464919, Example 131)
Affinity DataIC50: 2.81nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419738(US10464919, Example 76)
Affinity DataIC50: 2.86nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419731(US10464919, Example 69)
Affinity DataIC50: 3.04nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419802(US10464919, Example 186 | US10464919, Example 140)
Affinity DataIC50: 3.05nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419787(US10464919, Example 125)
Affinity DataIC50: 3.18nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419807(US10464919, Example 145)
Affinity DataIC50: 3.24nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419755(US10464919, Example 93)
Affinity DataIC50: 3.25nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419832(US10464919, Example 170)
Affinity DataIC50: 3.30nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419844(US10464919, Example 182)
Affinity DataIC50: 3.33nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419799(US10464919, Example 137)
Affinity DataIC50: 3.36nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419726(US10464919, Example 64)
Affinity DataIC50: 3.38nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419785(US10464919, Example 123)
Affinity DataIC50: 3.49nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419775(US10464919, Example 113)
Affinity DataIC50: 3.49nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419755(US10464919, Example 93)
Affinity DataIC50: 3.59nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419794(US10464919, Example 132)
Affinity DataIC50: 3.60nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419797(US10464919, Example 135)
Affinity DataIC50: 3.66nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419759(US10464919, Example 97)
Affinity DataIC50: 3.70nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419718(US10464919, Example 56)
Affinity DataIC50: 3.78nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetActivated CDC42 kinase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419723(US10464919, Example 61)
Affinity DataIC50: 3.80nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419763(US10464919, Example 101)
Affinity DataIC50: 3.87nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419785(US10464919, Example 123)
Affinity DataIC50: 3.92nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419844(US10464919, Example 182)
Affinity DataIC50: 4.02nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419797(US10464919, Example 135)
Affinity DataIC50: 4.04nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TNK1(Human)
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419796(US10464919, Example 134)
Affinity DataIC50: 4.15nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

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