Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 8772
TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419118(US10450321, Example 6 | 5-tert-Butyl-7-(3,3-difluo...)
Affinity DataKi:  211nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419117(US10450321, Example 5 | 2-{[5-tert-Butyl-7-(3,3-di...)
Affinity DataKi:  361nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419119(US10450321, Example 7 | 2-[[5-tert-Butyl-7-(3,3-di...)
Affinity DataKi:  421nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419116(US10450321, Example 4 | 5-tert-Butyl-7-(3,3-difluo...)
Affinity DataKi:  453nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419115(US10450321, Example 3 | (3S)-1-(5-tert-Butyl-2-{[2...)
Affinity DataKi:  529nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419114(US10450321, Example 2 | (2-{[5-tert-Butyl-7-(3,3-d...)
Affinity DataKi:  637nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419113(US10450321, Example 1 | 2-({5-tert-Butyl-7-[(3S)-3...)
Affinity DataKi:  1.17E+3nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419118(US10450321, Example 6 | 5-tert-Butyl-7-(3,3-difluo...)
Affinity DataKi:  4.88E+3nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419113(US10450321, Example 1 | 2-({5-tert-Butyl-7-[(3S)-3...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419114(US10450321, Example 2 | (2-{[5-tert-Butyl-7-(3,3-d...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419115(US10450321, Example 3 | (3S)-1-(5-tert-Butyl-2-{[2...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419116(US10450321, Example 4 | 5-tert-Butyl-7-(3,3-difluo...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419117(US10450321, Example 5 | 2-{[5-tert-Butyl-7-(3,3-di...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM419119(US10450321, Example 7 | 2-[[5-tert-Butyl-7-(3,3-di...)
Affinity DataKi: >1.00E+4nMAssay Description:The affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details
Go to US Patent