Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 8681
LigandPNGBDBM412665(US10399985, Example 3 | (2-Methyl-6-((1- methyl-4-...)
Affinity DataIC50: 1nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412696(US10399985, Example 8 | 6-(1-Methyl-4- phenyl-1H- ...)
Affinity DataIC50: 1nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412698(US10399985, Example 11 | (E)-2,3-Dimethyl-6-(2-(1-...)
Affinity DataIC50: 1.30nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412693(US10399985, Example 4 | 2,3-Dimethyl-5- ((1-methyl...)
Affinity DataIC50: 1.5nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412721(US10399985, Example 34 | 2,3,7,8-Tetramethyl-6- ((...)
Affinity DataIC50: 1.70nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412694(US10399985, Example 6 | (2-Cyclopropyl-6- ((1-meth...)
Affinity DataIC50: 1.90nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412702(US10399985, Example 16 | 2,3-Dimethyl-5-(2-(1- met...)
Affinity DataIC50: 2.40nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412713(US10399985, Example 27 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 3.30nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412733(US10399985, Example 46 | 2,3-Dimethyl-5-((1- methy...)
Affinity DataIC50: 3.40nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412701(US10399985, Example 15 | (2-Methyl-6-(2-(1- methyl...)
Affinity DataIC50: 3.40nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412716(US10399985, Example 30 | 3,8-Dimethyl-6-(2-(1-meth...)
Affinity DataIC50: 3.70nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412708(US10399985, Example 22 | 3-Methyl-6-[2-(1- methyl-...)
Affinity DataIC50: 5.40nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412705(US10399985, Example 19 | 2-(Difluoromethyl)-3- met...)
Affinity DataIC50: 6.40nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412719(US10399985, Example 32 | 2,3-Dimethyl-6-((1-methyl...)
Affinity DataIC50: 7.20nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412718(US10399985, Example 31 | N,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 8nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412709(US10399985, Example 23 | 2,3-Dimethyl-6-(2-(1-meth...)
Affinity DataIC50: 9.20nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412700(US10399985, Example 14 | 2,3,7,8-Tetramethyl-6- (2...)
Affinity DataIC50: 10.8nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412728(US10399985, Example 41 | 8-Methoxy-3-methyl- 6-((1...)
Affinity DataIC50: 11.8nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412697(US10399985, Example 10 | 2-Cyclopropyl-3- methyl-6...)
Affinity DataIC50: 12nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412699(US10399985, Example 12 | (E)-3-methyl-6-(2-(1- met...)
Affinity DataIC50: 13.8nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412703(US10399985, Example 17 | 3-Methyl-6-(2-(1- methyl-...)
Affinity DataIC50: 20.5nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412727(US10399985, Example 40 | 3-Methyl-6-((1-methyl- 4-...)
Affinity DataIC50: 23.7nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412707(US10399985, Example 21 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 27.7nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412711(US10399985, Example 25 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 32.3nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412715(US10399985, Example 29 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 33.2nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412723(US10399985, Example 36 | 3-Methyl-6-((1-methyl- 4-...)
Affinity DataIC50: 34.6nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412695(US10399985, Example 7 | 2- (Difluoromethyl)- 3-met...)
Affinity DataIC50: 46.6nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412731(US10399985, Example 44 | 2-[(1-Methyl-4-phenyl- im...)
Affinity DataIC50: 47nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412720(US10399985, Example 33 | 2,3-Dimethyl-6-((1- methy...)
Affinity DataIC50: 51.6nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412714(US10399985, Example 28 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 81.2nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412706(US10399985, Example 20 | 6-(2-(1-Methyl-4- phenyl-...)
Affinity DataIC50: 82.8nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412712(US10399985, Example 26 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 98.5nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412726(US10399985, Example 39 | 3-Methyl-6-((1-methyl- 4-...)
Affinity DataIC50: 114nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412725(US10399985, Example 38 | 2-Methyl-6-((1-methyl- 4-...)
Affinity DataIC50: 133nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412730(US10399985, Example 43 | (2-Cyclopropyl-6-((1- met...)
Affinity DataIC50: 167nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412724(US10399985, Example 37 | 2-Cyclopropyl-6-((1- meth...)
Affinity DataIC50: 169nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412722(US10399985, Example 35 | 2-Ethyl-3-methyl-6-((1- m...)
Affinity DataIC50: 264nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412732(US10399985, Example 45 | 6-((1-Methyl-4-phenyl- 1H...)
Affinity DataIC50: 328nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412729(US10399985, Example 42 | (3-Methyl-6-((1-methyl- 4...)
Affinity DataIC50: 363nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412704(US10399985, Example 18 | (2-Cyclopropyl-6-(2- (1-m...)
Affinity DataIC50: 656nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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LigandPNGBDBM412710(US10399985, Example 24 | 2,3-Dimethyl-6-(2-(1- met...)
Affinity DataIC50: 1.69E+3nMAssay Description:The following test was carried out in order to determine the activity of the compounds of the present invention. PDE10 activity of the compounds of t...More data for this Ligand-Target Pair
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Date in BDB:
7/27/2020
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