Compile Data Set for Download or QSAR
Report error Found 92 Enz. Inhib. hit(s) with all data for entry = 8680
TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 0.241nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412676(US10399979, Compound 17c)
Affinity DataIC50: 0.890nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412680(US10399979, Compound 17d)
Affinity DataIC50: 1.01nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412687(US10399979, Compound 18)
Affinity DataIC50: 1.02nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412674(US10399979, Compound 17a)
Affinity DataIC50: 1.07nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 1.09nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412676(US10399979, Compound 17c)
Affinity DataIC50: 1.09nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 1.42nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412675(US10399979, Compound 17b)
Affinity DataIC50: 1.65nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412680(US10399979, Compound 17d)
Affinity DataIC50: 1.81nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412673(US10399979, Compound 13c)
Affinity DataIC50: 1.91nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412674(US10399979, Compound 17a)
Affinity DataIC50: 1.93nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412676(US10399979, Compound 17c)
Affinity DataIC50: 2.24nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412687(US10399979, Compound 18)
Affinity DataIC50: 2.55nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412674(US10399979, Compound 17a)
Affinity DataIC50: 2.92nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412687(US10399979, Compound 18)
Affinity DataIC50: 3.12nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412690(US10399979, Compound 20a)
Affinity DataIC50: 3.37nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412675(US10399979, Compound 17b)
Affinity DataIC50: 3.57nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412674(US10399979, Compound 17a)
Affinity DataIC50: 4.23nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412687(US10399979, Compound 18)
Affinity DataIC50: 4.35nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412684(US10399979, Compound 17h)
Affinity DataIC50: 5.28nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412676(US10399979, Compound 17c)
Affinity DataIC50: 6.59nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412672(US10399979, Compound 13b)
Affinity DataIC50: 6.65nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412680(US10399979, Compound 17d)
Affinity DataIC50: 8.38nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412684(US10399979, Compound 17h)
Affinity DataIC50: 8.91nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412672(US10399979, Compound 13b)
Affinity DataIC50: 9.88nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412671(US10399979, Compound 13a)
Affinity DataIC50: 9.94nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 10.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412673(US10399979, Compound 13c)
Affinity DataIC50: 10.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412683(US10399979, Compound 17g)
Affinity DataIC50: 10.6nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412682(US10399979, Compound 17f)
Affinity DataIC50: 11.5nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412671(US10399979, Compound 13a)
Affinity DataIC50: 14.1nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412682(US10399979, Compound 17f)
Affinity DataIC50: 14.7nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412673(US10399979, Compound 13c)
Affinity DataIC50: 17.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412672(US10399979, Compound 13b)
Affinity DataIC50: 17.6nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412680(US10399979, Compound 17d)
Affinity DataIC50: 17.9nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412682(US10399979, Compound 17f)
Affinity DataIC50: 18.3nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
Go to US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412672(US10399979, Compound 13b)
Affinity DataIC50: 18.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412684(US10399979, Compound 17h)
Affinity DataIC50: 23.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412689(US10399979, Compound 19b)
Affinity DataIC50: 26.6nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412673(US10399979, Compound 13c)
Affinity DataIC50: 27.5nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK3(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412685(US10399979, Compound 17i)
Affinity DataIC50: 28.9nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412690(US10399979, Compound 20a)
Affinity DataIC50: 29.6nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412692(US10399979, Compound 21)
Affinity DataIC50: 30.2nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412682(US10399979, Compound 17f)
Affinity DataIC50: 32.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412681(US10399979, Compound 17e)
Affinity DataIC50: 37.1nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412681(US10399979, Compound 17e)
Affinity DataIC50: 37.5nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412683(US10399979, Compound 17g)
Affinity DataIC50: 37.9nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412675(US10399979, Compound 17b)
Affinity DataIC50: 39.4nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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TargetTyrosine-protein kinase JAK1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM412691(US10399979, Compound 20b)
Affinity DataIC50: 43.8nMAssay Description:Reagents used in JAK inhibition assay: Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
7/27/2020
Entry Details
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