Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 8629
TargetTransthyretin(Human)
Bsim Therapeutics

US Patent
LigandPNGBDBM408979(US10377729, Compound 2OH-PCB80)
Affinity DataIC50: 1.59E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetTransthyretin(Human)
Bsim Therapeutics

US Patent
LigandPNGBDBM408976(US10377729, Compound AT09-B00)
Affinity DataIC50: 2.02E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetTransthyretin(Human)
Bsim Therapeutics

US Patent
LigandPNGBDBM408980(Thyroxine | US10377729, T4)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
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TargetTransthyretin(Human)
Bsim Therapeutics

US Patent
LigandPNGBDBM408977(US10377729, Compound AT09-B06)
Affinity DataIC50: 2.49E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent

TargetTransthyretin(Human)
Bsim Therapeutics

US Patent
LigandPNGBDBM50197883(CHEBI:78538 | FX-1006 | Tafamidis | Vyndaqel | US1...)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro evaluation of inhibitory activity against WT-TTR amyloid fibril formation of AT09 and reference compounds. Reference compounds (thyroxine, t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
Go to US Patent